Scabfre
Generic Name
Permethrin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| scabfre 5 w cream | ৳ 55.00 | N/A |
Description
Overview of the medicine
Scabfre Cream contains Permethrin, an insecticide used to treat scabies and head lice. It works by paralyzing and killing mites and lice and their eggs.
Uses & Indications
Dosage
Adults
Apply a thin layer of cream from the head to the soles of the feet. Leave on for 8-14 hours, then wash off. One application is usually sufficient, but a second application may be needed after 7-14 days if living mites are still present.
Elderly
Same as adult dosage.
Renal_impairment
No specific dosage adjustment needed as systemic absorption is minimal.
How to Take
For external use only. Apply to clean, dry skin. Do not apply to open wounds or mucous membranes.
Mechanism of Action
Permethrin acts on the neuron membrane by disrupting the sodium channel current, causing delayed repolarization and subsequent paralysis and death of the parasite.
Pharmacokinetics
Onset
Relief of itching within hours to days; parasiticidal action within hours.
Excretion
Metabolites are primarily excreted in urine.
Half life
Approximately 24-48 hours (systemically absorbed portion).
Absorption
Minimal systemic absorption (less than 2%) occurs after topical application.
Metabolism
Rapidly hydrolyzed by esterases to inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to permethrin, other pyrethroids, or any component of the cream.
- •Infants under 2 months of age (for scabies treatment).
Drug Interactions
No significant drug interactions are expected due to minimal systemic absorption.
No specific drug interaction noted for topical permethrin due to very low systemic absorption.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose may result in increased local irritation. In case of accidental ingestion, symptomatic and supportive treatment should be given.
Pregnancy & Lactation
Generally considered safe for use in pregnancy and lactation, but use with caution and only if clearly needed.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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