Sinafort-B
Generic Name
Vitamin B Complex with Vitamin C
Manufacturer
Drug International Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sinafort b 5 mg tablet | ৳ 0.62 | ৳ 27.90 |
Description
Overview of the medicine
Sinafort-B 5 mg tablet is a multivitamin preparation containing a combination of B vitamins and Vitamin C. It is used to prevent or treat vitamin deficiencies caused by poor diet, certain illnesses, alcoholism, or pregnancy. B vitamins are essential for metabolism, nerve function, and red blood cell formation, while Vitamin C is an antioxidant crucial for immune function and collagen synthesis.
Uses & Indications
Dosage
Adults
Typically one tablet daily, or as directed by a physician.
Elderly
No specific dose adjustment required; usually one tablet daily.
Renal_impairment
Use with caution in severe renal impairment; consult a physician.
How to Take
Oral administration. Tablets should be swallowed whole with water, preferably with meals to minimize gastrointestinal upset.
Mechanism of Action
B vitamins act as coenzymes in various metabolic pathways, essential for converting food into energy, supporting nerve function, and DNA synthesis. Vitamin C is a powerful antioxidant that protects cells from damage by free radicals, boosts immune function, and is vital for collagen production, aiding in wound healing and maintaining healthy tissues.
Pharmacokinetics
Onset
Nutritional effects are gradual, building up with consistent use over days to weeks.
Excretion
Primarily renal excretion of unmetabolized vitamins and their metabolites.
Half life
Highly variable depending on the specific vitamin; water-soluble vitamins typically have short half-lives and are not stored extensively.
Absorption
Most B vitamins and Vitamin C are readily absorbed from the gastrointestinal tract, primarily in the small intestine.
Metabolism
Water-soluble vitamins are not extensively metabolized but utilized as coenzymes; excess is typically excreted.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Hypervitaminosis (rare with water-soluble vitamins, but theoretically possible with excessive intake)
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the efficacy of levodopa (used in Parkinson's disease).
Certain antibiotics (e.g., tetracyclines)
May interfere with absorption of some B vitamins. Separate administration times.
Folic acid antagonists (e.g., methotrexate)
May be affected by some B vitamins.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Overdose of water-soluble vitamins is rare due to renal excretion. However, extremely high doses of some B vitamins (e.g., Pyridoxine) can cause neuropathy. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased nutritional demands, but consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Hypervitaminosis (rare with water-soluble vitamins, but theoretically possible with excessive intake)
Drug Interactions
Levodopa
Pyridoxine (Vitamin B6) may reduce the efficacy of levodopa (used in Parkinson's disease).
Certain antibiotics (e.g., tetracyclines)
May interfere with absorption of some B vitamins. Separate administration times.
Folic acid antagonists (e.g., methotrexate)
May be affected by some B vitamins.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture.
Overdose
Overdose of water-soluble vitamins is rare due to renal excretion. However, extremely high doses of some B vitamins (e.g., Pyridoxine) can cause neuropathy. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased nutritional demands, but consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic
Clinical Trials
Limited clinical trials for general vitamin supplementation; efficacy based on established roles of individual vitamins.
Lab Monitoring
- Routine monitoring not usually required for general supplementation.
- In cases of suspected severe deficiency, specific vitamin levels may be tested.
Doctor Notes
- Advise patients on dietary sources of B vitamins and Vitamin C.
- Monitor for signs of deficiency or overdose in specific patient populations.
- Emphasize that supplements are not a substitute for a balanced diet.
Patient Guidelines
- Take regularly as directed.
- Do not exceed the recommended dose.
- Store in a cool, dry place.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Generally safe; not known to impair ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains.
- Engage in regular physical activity.
- Avoid excessive alcohol consumption.
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