Solo
Generic Name
solo-09-injection
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| solo 09 injection | ৳ 67.85 | N/A |
Description
Overview of the medicine
Solo-09 Injection is a potent non-steroidal anti-inflammatory drug (NSAID) administered parenterally for rapid relief of acute pain and inflammation.
Uses & Indications
Dosage
Adults
50 mg IM/IV every 8 hours as needed. Max 150 mg/day.
Elderly
Lower doses may be required; caution advised.
Renal_impairment
Dose adjustment necessary; monitor renal function.
How to Take
Administer deep intramuscularly or slowly intravenously over at least 15 seconds.
Mechanism of Action
Solo-09 acts by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain and inflammation.
Pharmacokinetics
Onset
15-30 minutes (IM/IV)
Excretion
Mainly renal, with some biliary excretion.
Half life
2-4 hours
Absorption
Rapidly and completely absorbed after intramuscular (IM) or intravenous (IV) administration.
Metabolism
Primarily hepatic, undergoes extensive first-pass metabolism.
Side Effects
Contraindications
- Hypersensitivity to NSAIDs
- Active gastrointestinal bleeding or ulceration
- Severe renal or hepatic impairment
- Third trimester of pregnancy
- Coronary artery bypass graft (CABG) surgery
Drug Interactions
Lithium
Increased plasma lithium levels.
Diuretics
Reduced diuretic and antihypertensive effects.
Anticoagulants
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, protected from light. Do not freeze.
Overdose
Symptoms may include lethargy, drowsiness, nausea, vomiting, epigastric pain. Management includes symptomatic and supportive care. Gastric lavage and activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy due to risk of premature ductus arteriosus closure. Use with caution during early pregnancy and lactation only if clearly needed and benefits outweigh risks.
Side Effects
Contraindications
- Hypersensitivity to NSAIDs
- Active gastrointestinal bleeding or ulceration
- Severe renal or hepatic impairment
- Third trimester of pregnancy
- Coronary artery bypass graft (CABG) surgery
Drug Interactions
Lithium
Increased plasma lithium levels.
Diuretics
Reduced diuretic and antihypertensive effects.
Anticoagulants
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, protected from light. Do not freeze.
Overdose
Symptoms may include lethargy, drowsiness, nausea, vomiting, epigastric pain. Management includes symptomatic and supportive care. Gastric lavage and activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Avoid during the third trimester of pregnancy due to risk of premature ductus arteriosus closure. Use with caution during early pregnancy and lactation only if clearly needed and benefits outweigh risks.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Hospitals, Clinics, Pharmacies
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Off-patent
Clinical Trials
Phase III clinical trials demonstrated significant efficacy in acute pain management with an acceptable safety profile.
Lab Monitoring
- Renal function (creatinine, BUN)
- Liver function tests (ALT, AST)
- Complete blood count (CBC)
Doctor Notes
- Monitor patients for signs of GI bleeding.
- Assess renal function periodically during extended therapy.
- Consider proton pump inhibitor co-administration in high-risk patients.
Patient Guidelines
- Do not exceed the prescribed dose.
- Report any unusual bleeding or bruising.
- Avoid alcohol while on this medication.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness. Patients should be advised not to drive or operate machinery if they experience these symptoms.
Lifestyle Advice
- Maintain adequate hydration.
- Inform your doctor about all other medications you are taking.
- Avoid activities requiring mental alertness if dizziness occurs.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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