solo
Generic Name
Xylometazoline Hydrochloride
Manufacturer
XYZ Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| solo 09 nasal drop | ৳ 25.00 | N/A |
Description
Overview of the medicine
Solo-09 Nasal Drop contains Xylometazoline Hydrochloride, which is a topical decongestant used to relieve nasal congestion caused by colds, allergies, and sinusitis. It works by constricting blood vessels in the nasal passages.
Uses & Indications
Dosage
Adults
1-2 drops into each nostril, 2-3 times daily, for a maximum of 3-5 consecutive days.
Elderly
Same as adults, but use with caution due to potential systemic effects.
Renal_impairment
No specific dosage adjustment required due to minimal systemic absorption.
How to Take
Clear nasal passages. Tilt head back slightly and apply drops into each nostril. Keep head tilted for a few moments. Do not exceed recommended dosage or duration of use.
Mechanism of Action
Xylometazoline is an alpha-adrenergic agonist that acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa, causing vasoconstriction. This leads to a reduction in swelling and congestion of the nasal passages, improving airflow.
Pharmacokinetics
Onset
Within 5-10 minutes.
Excretion
Mainly local action; any systemically absorbed drug is excreted via urine.
Half life
Approximately 5-10 hours, though systemic effects are minimal.
Absorption
Minimal systemic absorption after topical nasal administration.
Metabolism
Not extensively metabolized locally; any absorbed drug is primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to xylometazoline or any other component.
- Narrow-angle glaucoma.
- Patients who have undergone transsphenoidal hypophysectomy or other surgery exposing the dura mater.
- Children under 2 years of age.
Drug Interactions
Tricyclic Antidepressants (TCAs)
May potentiate the pressor effects of xylometazoline.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may lead to a hypertensive crisis. Avoid use within 14 days of stopping MAOIs.
Storage
Store in a cool and dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe headache, palpitations, bradycardia, hypertension, and CNS depression in children. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and under medical supervision. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to xylometazoline or any other component.
- Narrow-angle glaucoma.
- Patients who have undergone transsphenoidal hypophysectomy or other surgery exposing the dura mater.
- Children under 2 years of age.
Drug Interactions
Tricyclic Antidepressants (TCAs)
May potentiate the pressor effects of xylometazoline.
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may lead to a hypertensive crisis. Avoid use within 14 days of stopping MAOIs.
Storage
Store in a cool and dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe headache, palpitations, bradycardia, hypertension, and CNS depression in children. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and under medical supervision. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Generic
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of Xylometazoline Hydrochloride in relieving nasal congestion when used as directed.
Lab Monitoring
- No routine laboratory monitoring is typically required for topical xylometazoline use.
Doctor Notes
- Emphasize short-term use (max 3-5 days) to patients.
- Advise against use in patients with severe cardiovascular disease or uncontrolled hypertension without prior consultation.
- Educate patients on proper administration technique to ensure effective delivery and minimize systemic absorption.
Patient Guidelines
- Do not use for more than 3-5 consecutive days to avoid rebound congestion (rhinitis medicamentosa).
- Consult a doctor if symptoms persist or worsen after 5 days.
- Avoid sharing the nasal drop bottle with others to prevent the spread of infection.
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally, solo-09 Nasal Drop has no or negligible influence on the ability to drive and use machines. However, if systemic side effects occur, caution is advised.
Lifestyle Advice
- Stay hydrated by drinking plenty of fluids.
- Avoid exposure to irritants like smoke or strong odors.
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