Sulforid
Generic Name
Sulforid-4-mg-tablet
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sulforid 4 mg tablet | ৳ 13.00 | ৳ 130.00 |
Description
Overview of the medicine
Sulforid 4 mg Tablet is an anti-inflammatory drug used to relieve pain and inflammation associated with various musculoskeletal and rheumatic conditions.
Uses & Indications
Dosage
Adults
4 mg once daily, or 2 mg twice daily, with or after food.
Elderly
Start with 2 mg once daily, adjust based on response and tolerability.
Renal_impairment
Dose adjustment may be required; consult physician. Not recommended for severe renal impairment.
How to Take
Take orally with a glass of water, with or after food to minimize gastrointestinal upset.
Mechanism of Action
Sulforid acts by inhibiting the enzyme cyclooxygenase (COX-2), which is responsible for the synthesis of prostaglandins, mediators of pain and inflammation.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly excreted via urine, with some biliary excretion.
Half life
Approximately 6-8 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, peak plasma concentration reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily via CYP enzymes.
Side Effects
Contraindications
- Known hypersensitivity to Sulforid or other NSAIDs.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Active peptic ulcer or gastrointestinal bleeding.
- Severe heart failure, renal failure, or hepatic failure.
- Third trimester of pregnancy.
Drug Interactions
Lithium
Increased lithium plasma levels.
Corticosteroids
Increased risk of GI ulceration.
Diuretics/ACE inhibitors
Reduced hypotensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, nausea, vomiting, epigastric pain, and gastrointestinal bleeding. Management involves supportive care and symptomatic treatment. Gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Not recommended during the third trimester of pregnancy due to potential fetal harm. Use with caution during the first and second trimesters only if clearly needed. Avoid during lactation as it may pass into breast milk.
Side Effects
Contraindications
- Known hypersensitivity to Sulforid or other NSAIDs.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Active peptic ulcer or gastrointestinal bleeding.
- Severe heart failure, renal failure, or hepatic failure.
- Third trimester of pregnancy.
Drug Interactions
Lithium
Increased lithium plasma levels.
Corticosteroids
Increased risk of GI ulceration.
Diuretics/ACE inhibitors
Reduced hypotensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, nausea, vomiting, epigastric pain, and gastrointestinal bleeding. Management involves supportive care and symptomatic treatment. Gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Not recommended during the third trimester of pregnancy due to potential fetal harm. Use with caution during the first and second trimesters only if clearly needed. Avoid during lactation as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patented
Clinical Trials
Extensive Phase III clinical trials demonstrated significant efficacy in reducing pain and inflammation with an acceptable safety profile.
Lab Monitoring
- Monitor complete blood count, liver function tests, and renal function tests periodically during long-term therapy.
Doctor Notes
- Monitor for signs of GI bleeding or cardiovascular adverse events, especially in patients with pre-existing risks.
- Consider lowest effective dose for the shortest duration.
Patient Guidelines
- Take with food or milk to reduce stomach upset.
- Do not exceed the recommended dose.
- Inform your doctor if you experience any unusual bleeding, persistent stomach pain, or swelling.
- Avoid alcohol while taking this medicine.
- Long-term use may require regular monitoring.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness. Exercise caution when driving or operating machinery until you know how Sulforid affects you.
Lifestyle Advice
- Maintain a healthy diet and regular exercise, if applicable to your condition.
- Avoid smoking, as it can worsen inflammation and increase cardiovascular risk.
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Global Brand Names
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