Superpime

Superpime 500 mg Injection is administered via slow intravenous infusion (over 30 minutes) or deep intramuscular injection. For IV administration, the powder should be reconstituted with an appropriate diluent (e.g., Sterile Water for Injection, 5% Dextrose Injection) and then diluted further before infusion. For IM administration, reconstitute with Sterile Water for Injection or 0.5% Lidocaine HCl Solution.

Cefepime acts by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) located in the bacterial cell wall, which interferes with the transpeptidation step of peptidoglycan synthesis, leading to cell wall defects and bacterial cell lysis.

• Known hypersensitivity to cefepime or any other cephalosporin antibiotics.
• Known hypersensitivity to penicillin or other beta-lactam antibiotics (due to potential cross-reactivity).
• History of severe immediate hypersensitivity reactions to beta-lactam antibiotics.

Store unreconstituted vials at controlled room temperature (20-25°C) and protect from light. After reconstitution, refer to specific manufacturer instructions for storage duration and temperature (usually stable for 24 hours at room temperature or up to 7 days under refrigeration).

Symptoms of overdose may include encephalopathy (impaired consciousness, confusion, hallucinations, stupor, coma), myoclonus, and seizures. Management should be supportive, including discontinuation of the drug. Hemodialysis may be useful in facilitating the removal of cefepime from the body, especially in patients with impaired renal function.

Pregnancy Category B. Animal reproduction studies have not demonstrated a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Cefepime is excreted in human breast milk in small quantities; caution should be exercised when administered to a nursing woman.

• Known hypersensitivity to cefepime or any other cephalosporin antibiotics.
• Known hypersensitivity to penicillin or other beta-lactam antibiotics (due to potential cross-reactivity).
• History of severe immediate hypersensitivity reactions to beta-lactam antibiotics.

Store unreconstituted vials at controlled room temperature (20-25°C) and protect from light. After reconstitution, refer to specific manufacturer instructions for storage duration and temperature (usually stable for 24 hours at room temperature or up to 7 days under refrigeration).

Symptoms of overdose may include encephalopathy (impaired consciousness, confusion, hallucinations, stupor, coma), myoclonus, and seizures. Management should be supportive, including discontinuation of the drug. Hemodialysis may be useful in facilitating the removal of cefepime from the body, especially in patients with impaired renal function.

Pregnancy Category B. Animal reproduction studies have not demonstrated a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Cefepime is excreted in human breast milk in small quantities; caution should be exercised when administered to a nursing woman.