Telmicard
Generic Name
Telmisartan
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| telmicard 40 mg tablet | ৳ 8.00 | ৳ 112.00 |
Description
Overview of the medicine
Telmicard 40 mg Tablet contains Telmisartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension) and to reduce the risk of cardiovascular events like heart attack or stroke in patients at high risk.
Uses & Indications
Dosage
Adults
The usual recommended dose is 40 mg once daily. If blood pressure is not controlled, the dose may be increased to a maximum of 80 mg once daily.
Elderly
No dosage adjustment is generally needed for elderly patients.
Renal_impairment
No dosage adjustment is required for patients with mild to moderate renal impairment. Caution is advised in severe renal impairment.
How to Take
Telmicard tablets should be taken orally once daily with or without food. It should be swallowed with water.
Mechanism of Action
Telmisartan selectively blocks the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle and the adrenal gland. This blockade inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to vasodilation and reduction in blood pressure.
Pharmacokinetics
Onset
Antihypertensive effect starts within 3 hours. Maximum blood pressure reduction is generally attained after 4 to 8 weeks of therapy.
Excretion
Almost exclusively eliminated in feces (approximately 97%) via biliary excretion. Less than 1% is excreted in urine.
Half life
Approximately 24 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract. Absolute bioavailability is dose-dependent, approximately 42% for a 40 mg dose.
Metabolism
Primarily metabolized by conjugation to form an acylglucuronide, which is pharmacologically inactive. Minimal metabolism by cytochrome P450 system.
Side Effects
Contraindications
- Hypersensitivity to the active substance or to any of the excipients.
- Second and third trimesters of pregnancy.
- Biliary obstructive disorders.
- Severe hepatic impairment.
- Concomitant use of aliskiren in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73 m²).
Drug Interactions
Digoxin
Increased plasma concentrations of digoxin may occur; monitor digoxin levels.
Lithium
Increased serum lithium concentrations and toxicity have been reported. Monitor lithium levels.
Aliskiren
Concomitant use is contraindicated in diabetic or renally impaired patients due to increased risk of hyperkalemia, hypotension, and renal impairment.
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
May reduce the antihypertensive effect of Telmisartan and increase the risk of renal impairment.
Potassium-sparing diuretics, potassium supplements, or other agents that increase potassium levels
May lead to hyperkalemia. Monitor serum potassium levels.
Storage
Store in a dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
The most likely manifestations of overdose would be hypotension, dizziness, and tachycardia; bradycardia could occur from parasympathetic stimulation. Treatment is symptomatic and supportive. Telmisartan is not removed by hemodialysis.
Pregnancy & Lactation
Telmicard is contraindicated during the second and third trimesters of pregnancy and should not be used in the first trimester. It is not recommended during breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to the active substance or to any of the excipients.
- Second and third trimesters of pregnancy.
- Biliary obstructive disorders.
- Severe hepatic impairment.
- Concomitant use of aliskiren in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73 m²).
Drug Interactions
Digoxin
Increased plasma concentrations of digoxin may occur; monitor digoxin levels.
Lithium
Increased serum lithium concentrations and toxicity have been reported. Monitor lithium levels.
Aliskiren
Concomitant use is contraindicated in diabetic or renally impaired patients due to increased risk of hyperkalemia, hypotension, and renal impairment.
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
May reduce the antihypertensive effect of Telmisartan and increase the risk of renal impairment.
Potassium-sparing diuretics, potassium supplements, or other agents that increase potassium levels
May lead to hyperkalemia. Monitor serum potassium levels.
Storage
Store in a dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
The most likely manifestations of overdose would be hypotension, dizziness, and tachycardia; bradycardia could occur from parasympathetic stimulation. Treatment is symptomatic and supportive. Telmisartan is not removed by hemodialysis.
Pregnancy & Lactation
Telmicard is contraindicated during the second and third trimesters of pregnancy and should not be used in the first trimester. It is not recommended during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Available in pharmacies and hospitals
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Telmisartan has been extensively studied in large clinical trials (e.g., ONTARGET, TRANSCEND) demonstrating its efficacy in hypertension and cardiovascular risk reduction.
Lab Monitoring
- Serum potassium levels (especially in patients with renal impairment or those taking other potassium-increasing drugs).
- Renal function (creatinine, BUN) periodically.
Doctor Notes
- Regularly monitor blood pressure and renal function (eGFR, serum creatinine, potassium) in patients.
- Advise female patients of childbearing potential about the risks during pregnancy and the need for effective contraception.
- Caution with concomitant use of NSAIDs or potassium-sparing diuretics due to increased risk of renal impairment and hyperkalemia.
Patient Guidelines
- Take Telmicard exactly as prescribed by your doctor.
- Do not stop taking Telmicard without consulting your doctor, even if you feel well.
- Inform your doctor about all other medications, supplements, and herbal products you are taking.
- Report any unusual side effects, especially swelling of the face, lips, tongue, or throat.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Telmicard may cause dizziness or drowsiness, especially at the start of treatment or when changing dose. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Maintain a healthy diet low in sodium and saturated fats.
- Engage in regular physical activity as advised by your doctor.
- Limit alcohol consumption and avoid smoking.
- Monitor your blood pressure regularly at home.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Telmicard Brand
Other medicines available under the same brand name
