Telsan
Generic Name
Telmisartan
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| telsan 40 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Telsan (Telmisartan) is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension) and to reduce the risk of cardiovascular events in certain high-risk patients.
Uses & Indications
Dosage
Adults
Usually 40 mg once daily. May be increased to a maximum of 80 mg once daily if needed.
Elderly
No dosage adjustment is generally required for elderly patients.
Renal_impairment
No dosage adjustment required for mild to moderate renal impairment. For severe impairment, caution is advised.
How to Take
Oral administration, once daily, with or without food.
Mechanism of Action
Telmisartan selectively blocks the binding of angiotensin II to the AT1 receptor, which prevents vasoconstriction and aldosterone secretion, leading to a reduction in blood pressure.
Pharmacokinetics
Onset
Peak plasma concentrations are reached in 0.5-1 hour.
Excretion
Primarily excreted unchanged in feces (over 97%), with minimal renal excretion.
Half life
Approximately 24 hours.
Absorption
Rapidly absorbed, with absolute bioavailability ranging from 42% (40 mg) to 58% (160 mg).
Metabolism
Undergoes conjugation to form a pharmacologically inactive acylglucuronide.
Side Effects
Contraindications
- Hypersensitivity to telmisartan or any component of the product
- Pregnancy (second and third trimesters)
- Lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Concomitant use with aliskiren in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73 m²)
Drug Interactions
NSAIDs
Reduced antihypertensive effect, potential for increased renal impairment.
Digoxin
Increased plasma concentrations of digoxin.
Lithium
Increased serum lithium concentrations and toxicity.
Diuretics
Enhanced hypotensive effect.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms of overdose include hypotension, dizziness, and tachycardia. Treatment is symptomatic and supportive. Telmisartan is not removed by hemodialysis.
Pregnancy & Lactation
Contraindicated in the second and third trimesters of pregnancy due to fetal toxicity. Not recommended during lactation.
Side Effects
Contraindications
- Hypersensitivity to telmisartan or any component of the product
- Pregnancy (second and third trimesters)
- Lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Concomitant use with aliskiren in patients with diabetes mellitus or renal impairment (GFR < 60 mL/min/1.73 m²)
Drug Interactions
NSAIDs
Reduced antihypertensive effect, potential for increased renal impairment.
Digoxin
Increased plasma concentrations of digoxin.
Lithium
Increased serum lithium concentrations and toxicity.
Diuretics
Enhanced hypotensive effect.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms of overdose include hypotension, dizziness, and tachycardia. Treatment is symptomatic and supportive. Telmisartan is not removed by hemodialysis.
Pregnancy & Lactation
Contraindicated in the second and third trimesters of pregnancy due to fetal toxicity. Not recommended during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Available in all pharmacies in Bangladesh
Approval Status
Approved by DGDA/FDA
Patent Status
Patent expired (generic available)
Clinical Trials
ACTIVE, ONTARGET, TRANSCEND were major clinical trials involving telmisartan, demonstrating its efficacy in reducing cardiovascular events.
Lab Monitoring
- Renal function (creatinine, BUN)
- Serum electrolytes (potassium)
- Liver function tests
Doctor Notes
- Counsel patients on the importance of adherence to therapy, even if asymptomatic.
- Monitor renal function and serum potassium, especially in patients with pre-existing renal impairment or those on concomitant diuretics.
- Not for use during pregnancy, especially in the 2nd and 3rd trimesters.
Patient Guidelines
- Take Telsan exactly as prescribed by your doctor.
- Do not stop taking Telsan without consulting your doctor, even if you feel well.
- Report any swelling of the face, lips, tongue, or throat to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or fatigue, especially at the start of treatment. Patients should be cautioned about operating machinery or driving until they know how Telsan affects them.
Lifestyle Advice
- Maintain a healthy diet low in sodium and saturated fats.
- Engage in regular physical activity.
- Avoid smoking and limit alcohol consumption.
- Monitor blood pressure regularly at home.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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