Tenoxim
Generic Name
Tenoxicam
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tenoxim 20 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class, used to relieve pain, inflammation, and stiffness caused by various musculoskeletal and joint disorders.
Uses & Indications
Dosage
Adults
20 mg once daily.
Elderly
Lower initial dose may be considered; careful monitoring required.
Renal_impairment
Dosage adjustment may be necessary; monitor renal function.
How to Take
Take orally, preferably with or after food to minimize gastrointestinal upset. Swallow the tablet whole with a glass of water.
Mechanism of Action
Tenoxicam inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever.
Pharmacokinetics
Onset
Pain relief usually within 30 minutes to 1 hour.
Excretion
Mainly excreted via urine (two-thirds) and feces (one-third) as inactive metabolites.
Half life
Approximately 60-75 hours.
Absorption
Well absorbed from the gastrointestinal tract; peak plasma concentrations reached within 2 hours.
Metabolism
Extensively metabolized in the liver, primarily by hydroxylation.
Side Effects
Contraindications
- •Hypersensitivity to tenoxicam or other NSAIDs
- •Active gastrointestinal ulceration, bleeding, or perforation
- •Severe heart failure
- •Severe renal or hepatic impairment
- •Third trimester of pregnancy
- •Aspirin-induced asthma or urticaria
Drug Interactions
Lithium
Increased plasma lithium levels.
Methotrexate
Increased methotrexate toxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration or bleeding.
Diuretics and ACE inhibitors
Reduced hypotensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy. Management involves symptomatic and supportive treatment; gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Contraindicated in the third trimester of pregnancy. Use during other trimesters only if clearly needed and benefits outweigh risks. Not recommended during breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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