Adults

Apply a thin layer of cream to the affected skin area and surrounding skin once or twice daily. Treatment duration is typically 1 week for tinea pedis, tinea cruris, tinea corporis, and 2 weeks for pityriasis versicolor.

Elderly

No specific dosage adjustment is required for elderly patients. Use as per adult dosage.

Renal_impairment

No dosage adjustment necessary as systemic absorption is minimal.

Onset

Clinical improvement is often seen within a few days, but the full course of treatment should be completed. Mycological cure may take longer.

Excretion

Minimal systemic excretion due to low absorption. Metabolites are primarily excreted in urine after oral administration.

Half life

Due to minimal systemic absorption, the systemic half-life is not clinically relevant for topical use. For oral terbinafine, the elimination half-life is about 17-20 hours.

Absorption

Systemic absorption of terbinafine from topical application is minimal (less than 5%).

Metabolism

Minimal metabolism at the site of topical application. Systemically absorbed drug is metabolized in the liver.

Other topical preparations

Avoid concurrent use of other topical medications on the same affected area without consulting a doctor, as it may alter absorption or efficacy.