Tetrazin
Generic Name
Tetrazin 25 mg Tablet
Manufacturer
Alpha Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tetrazin 25 mg tablet | ৳ 35.00 | ৳ 350.00 |
Description
Overview of the medicine
Tetrazin 25 mg Tablet is an antihistamine used to relieve symptoms of allergic reactions such as itching, sneezing, watery eyes, and runny nose. It may also have mild sedative effects.
Uses & Indications
Dosage
Adults
25 mg orally, 1-2 times daily or as directed by physician. For insomnia, 25-50 mg at bedtime.
Elderly
Initiate with a lower dose (e.g., 12.5 mg) and adjust based on response and tolerability due to increased sensitivity and potential for adverse effects.
Renal_impairment
Dose adjustment may be necessary. Use with caution in patients with moderate to severe renal impairment. Consult physician.
How to Take
Take orally with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew.
Mechanism of Action
Tetrazin works by blocking the action of histamine, a natural substance in the body that causes allergic symptoms. It selectively blocks peripheral H1 receptors, thereby reducing allergic responses.
Pharmacokinetics
Onset
Onset of action within 30-60 minutes.
Excretion
Excreted mainly via urine, with some fecal excretion.
Half life
Plasma half-life of approximately 6-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Tetrazin or any components of the tablet
- Acute asthma attacks
- Narrow-angle glaucoma
- Urinary retention
Drug Interactions
CNS Depressants (e.g., alcohol, sedatives, hypnotics)
May potentiate the sedative effects of Tetrazin, leading to increased drowsiness and impaired coordination.
Anticholinergics (e.g., atropine, certain antidepressants)
May enhance anticholinergic side effects such as dry mouth, blurred vision, and urinary retention.
Storage
Store below 25°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, confusion, dizziness, blurred vision, dry mouth, urinary retention, and in severe cases, seizures or coma. Seek immediate medical attention.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Not recommended during breastfeeding as it may pass into breast milk and cause drowsiness in the infant. Consult a healthcare professional.
Side Effects
Contraindications
- Hypersensitivity to Tetrazin or any components of the tablet
- Acute asthma attacks
- Narrow-angle glaucoma
- Urinary retention
Drug Interactions
CNS Depressants (e.g., alcohol, sedatives, hypnotics)
May potentiate the sedative effects of Tetrazin, leading to increased drowsiness and impaired coordination.
Anticholinergics (e.g., atropine, certain antidepressants)
May enhance anticholinergic side effects such as dry mouth, blurred vision, and urinary retention.
Storage
Store below 25°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe drowsiness, confusion, dizziness, blurred vision, dry mouth, urinary retention, and in severe cases, seizures or coma. Seek immediate medical attention.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Not recommended during breastfeeding as it may pass into breast milk and cause drowsiness in the infant. Consult a healthcare professional.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Available in pharmacies nationwide
Approval Status
DGDA Approved
Patent Status
Generic Available
Clinical Trials
Clinical trials have evaluated the efficacy and safety of Tetrazin in managing allergic symptoms and for its sedative properties.
Lab Monitoring
- No routine lab monitoring is generally required for Tetrazin 25 mg Tablet under normal use.
Doctor Notes
- Advise patients about potential drowsiness and to avoid activities requiring alertness.
- Assess for concomitant use of other CNS depressants or anticholinergic medications.
- Consider lower doses in elderly or renally impaired patients.
Patient Guidelines
- Do not drive or operate heavy machinery if you experience drowsiness.
- Avoid alcohol while taking this medicine.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Tetrazin may cause drowsiness, dizziness, and impaired coordination. Patients should be warned against engaging in activities requiring mental alertness, such as driving a motor vehicle or operating hazardous machinery.
Lifestyle Advice
- Maintain good hydration.
- Avoid activities that require high mental alertness immediately after taking the medicine.
- Avoid exposure to known allergens.
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Global Brand Names
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