Tomycin
Generic Name
Tobramycin 0.3% Ophthalmic Solution
Manufacturer
XYZ Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tomycin 03 eye drop | ৳ 90.00 | N/A |
Description
Overview of the medicine
Tobramycin is an aminoglycoside antibiotic used to treat bacterial infections of the eye. It is effective against a wide range of gram-negative and some gram-positive bacteria.
Uses & Indications
Dosage
Adults
Mild to moderate infections: 1-2 drops into the affected eye(s) every 4-6 hours. Severe infections: 2 drops into the affected eye(s) every hour until improvement, then reduce frequency.
Elderly
No specific dosage adjustment required.
Renal_impairment
No specific dosage adjustment required for topical ophthalmic use.
How to Take
For ophthalmic use only. Tilt head back, pull down the lower eyelid to form a pouch, instill the drops into the pouch. Close the eye gently for 1-2 minutes. Avoid touching the dropper tip to any surface.
Mechanism of Action
Tobramycin exerts its bactericidal effect by irreversibly binding to the 30S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis.
Pharmacokinetics
Onset
Rapid onset of action, typically within minutes.
Excretion
Primarily excreted unchanged via the kidneys if absorbed systemically, but local excretion through tears.
Half life
Not significant systemically; locally, drug clears with tear turnover.
Absorption
Minimal systemic absorption following ocular administration.
Metabolism
Not significantly metabolized after topical ocular administration.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any component of the formulation
- Viral or fungal eye infections
Drug Interactions
Systemic aminoglycosides
Increased risk of ototoxicity/nephrotoxicity if significant systemic absorption occurs (rare with ophthalmic use).
Other ophthalmic medications
If using multiple ophthalmic medications, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Do not freeze. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, systemic overdose is unlikely. Local irritation may occur with excessive topical use. Symptomatic and supportive treatment.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Tobramycin is excreted in breast milk; caution advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any component of the formulation
- Viral or fungal eye infections
Drug Interactions
Systemic aminoglycosides
Increased risk of ototoxicity/nephrotoxicity if significant systemic absorption occurs (rare with ophthalmic use).
Other ophthalmic medications
If using multiple ophthalmic medications, administer them at least 5 minutes apart.
Storage
Store at room temperature (below 30°C). Do not freeze. Keep out of reach of children.
Overdose
Due to minimal systemic absorption, systemic overdose is unlikely. Local irritation may occur with excessive topical use. Symptomatic and supportive treatment.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Tobramycin is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months for unopened bottle. Discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities worldwide (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of tobramycin ophthalmic solution in treating bacterial eye infections.
Lab Monitoring
- Not routinely required for topical ophthalmic use.
Doctor Notes
- Emphasize proper administration technique to patients.
- Monitor for signs of superinfection or lack of improvement.
- Advise patients not to wear contact lenses during treatment.
Patient Guidelines
- Wash hands before and after use.
- Do not touch the dropper tip to any surface.
- Remove contact lenses before application and wait at least 15 minutes before reinserting.
- Do not share eye drops with others.
Missed Dose Advice
If a dose is missed, apply it as soon as possible. If it is almost time for the next dose, skip the missed dose and return to the regular dosing schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision. Avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid rubbing eyes.
- Maintain good ocular hygiene.
- Wear protective eyewear in dusty or irritating environments.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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