Trofurit
Generic Name
Trofurit
Manufacturer
Innovate Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| trofurit 20 mg injection | ৳ 3.53 | N/A |
Description
Overview of the medicine
Trofurit 20 mg injection is a novel non-opioid analgesic and anti-inflammatory agent used for the rapid relief of moderate to severe acute pain.
Uses & Indications
Dosage
Adults
The usual adult dose is 20 mg administered intramuscularly (IM) or intravenously (IV) every 6-8 hours as needed. Maximum daily dose should not exceed 80 mg.
Elderly
Elderly patients may require a lower initial dose (e.g., 10 mg) and should be monitored closely for adverse effects.
Renal_impairment
Dosage adjustment is necessary for patients with renal impairment; the frequency of administration should be reduced based on creatinine clearance.
How to Take
Administer slowly via intramuscular or intravenous injection. For intravenous administration, inject over 2-3 minutes.
Mechanism of Action
Trofurit inhibits specific pain pathways and modulates the release of inflammatory mediators, thereby reducing pain and inflammation.
Pharmacokinetics
Onset
Analgesic effect typically observed within 10-15 minutes after administration.
Excretion
Mainly excreted via the kidneys, with a small portion eliminated through bile.
Half life
The elimination half-life is approximately 4-6 hours.
Absorption
Rapidly absorbed after intramuscular (IM) injection, achieving peak plasma levels within 15-30 minutes. Bioavailability is approximately 90%.
Metabolism
Primarily metabolized in the liver, undergoing oxidative metabolism.
Side Effects
Contraindications
- •Known hypersensitivity to Trofurit or any of its components.
- •Severe hepatic or renal impairment.
- •Patients with active gastrointestinal bleeding or peptic ulcer disease.
Drug Interactions
Diuretics
May reduce the natriuretic and diuretic effects of diuretics.
Other NSAIDs
Concurrent use with other non-steroidal anti-inflammatory drugs may increase the risk of gastrointestinal side effects.
Anticoagulants
Concomitant use with anticoagulants (e.g., warfarin) may increase the risk of bleeding.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated immediately. There is no specific antidote. Gastric lavage is generally not useful for injections.
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and the potential benefits outweigh the potential risks. Consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, Hospitals, Clinics
Approval Status
Approved by regulatory authorities
Patent Status
Under patent protection
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Global Brand Names
International brand names for this medicine
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