Ulrif
Generic Name
Ulrif
Manufacturer
Globex Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ulrif 1 gm suspension | ৳ 400.00 | N/A |
Description
Overview of the medicine
Ulrif is a broad-spectrum antibiotic used to treat various bacterial infections, including those of the respiratory tract, urinary tract, and skin.
Uses & Indications
Dosage
Adults
250 mg capsule orally twice daily for 7-10 days, depending on the severity and type of infection.
Elderly
No specific dose adjustment required for elderly patients unless there is severe renal impairment. Monitor renal function.
Renal_impairment
Dosage reduction recommended in severe renal impairment (Creatinine Clearance < 30 mL/min). Consult a physician for specific dosage.
How to Take
Ulrif capsules can be taken with or without food. It is crucial to complete the full prescribed course of treatment, even if symptoms improve.
Mechanism of Action
Ulrif acts by inhibiting bacterial cell wall synthesis, leading to osmotic instability and subsequent bacterial cell lysis and death.
Pharmacokinetics
Onset
Clinical effects typically observed within 1-2 hours of the first dose.
Excretion
Mainly excreted via kidneys in urine, with a small portion excreted in feces.
Half life
Approximately 3-4 hours in healthy adults, which may be prolonged in renal impairment.
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 1-2 hours after oral administration.
Metabolism
Primarily hepatic metabolism to inactive metabolites. Minimal first-pass metabolism.
Side Effects
Contraindications
- Known hypersensitivity to Ulrif or any components of the formulation.
- History of severe allergic reactions to other beta-lactam antibiotics (e.g., penicillins, other cephalosporins).
Drug Interactions
Probenecid
May increase Ulrif plasma levels by reducing renal tubular secretion, potentially increasing its efficacy and side effects.
Aminoglycosides
Potential for synergistic bactericidal effect but also increased risk of nephrotoxicity.
Oral Anticoagulants (e.g., Warfarin)
May enhance the anticoagulant effect, increasing the risk of bleeding. Close monitoring of INR is recommended.
Storage
Store below 30°C in a dry place, protected from moisture and direct sunlight. Keep out of reach of children.
Overdose
In cases of overdose, gastric lavage or activated charcoal may be considered. Management is symptomatic and supportive. Hemodialysis may be useful in severe cases.
Pregnancy & Lactation
Pregnancy category B. Use with caution during pregnancy; consult a doctor. Excreted in breast milk in small amounts; generally considered safe for breastfeeding, but observe the infant for adverse effects.
Side Effects
Contraindications
- Known hypersensitivity to Ulrif or any components of the formulation.
- History of severe allergic reactions to other beta-lactam antibiotics (e.g., penicillins, other cephalosporins).
Drug Interactions
Probenecid
May increase Ulrif plasma levels by reducing renal tubular secretion, potentially increasing its efficacy and side effects.
Aminoglycosides
Potential for synergistic bactericidal effect but also increased risk of nephrotoxicity.
Oral Anticoagulants (e.g., Warfarin)
May enhance the anticoagulant effect, increasing the risk of bleeding. Close monitoring of INR is recommended.
Storage
Store below 30°C in a dry place, protected from moisture and direct sunlight. Keep out of reach of children.
Overdose
In cases of overdose, gastric lavage or activated charcoal may be considered. Management is symptomatic and supportive. Hemodialysis may be useful in severe cases.
Pregnancy & Lactation
Pregnancy category B. Use with caution during pregnancy; consult a doctor. Excreted in breast milk in small amounts; generally considered safe for breastfeeding, but observe the infant for adverse effects.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture when stored under recommended conditions.
Availability
Available in all pharmacies in Bangladesh
Approval Status
Approved by DGDA
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Extensive Phase III clinical trials demonstrated Ulrif's efficacy and safety in various bacterial infections across diverse patient populations. Post-marketing surveillance continues to affirm its favorable safety profile.
Lab Monitoring
- Renal function tests (for prolonged therapy or in patients with pre-existing renal impairment)
- Liver function tests (for prolonged therapy or in patients with hepatic dysfunction)
- Complete Blood Count (CBC)
Doctor Notes
- Emphasize adherence to the full antibiotic course to prevent resistance development and ensure complete eradication.
- Counsel patients on potential allergic reactions, especially those with a history of penicillin allergy; have epinephrine readily available.
- Monitor for signs of C. difficile-associated diarrhea in patients presenting with prolonged or severe diarrhea post-antibiotic treatment.
Patient Guidelines
- Complete the entire course of medication as prescribed, even if you feel better.
- Do not stop taking Ulrif prematurely without consulting your doctor.
- Report any severe or persistent side effects to your healthcare provider immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Ulrif generally does not impair the ability to drive or operate machinery. However, if you experience dizziness or other side effects that affect your concentration, avoid these activities.
Lifestyle Advice
- Maintain good personal hygiene to prevent reinfection.
- Drink plenty of fluids to stay hydrated, especially if experiencing diarrhea.
- Avoid self-medication and always consult a doctor for diagnosis and treatment.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Ulrif Brand
Other medicines available under the same brand name
