Unilor
Generic Name
Loratadine
Manufacturer
Reputable Pharmaceutical Company
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| unilor 25 mg syrup | ৳ 30.00 | N/A |
Description
Overview of the medicine
Unilor 25 mg syrup is an antihistamine used to relieve symptoms of allergies such as sneezing, runny nose, itching, and watery eyes. It is also helpful in the treatment of chronic urticaria (hives).
Uses & Indications
Dosage
Adults
Typically 10 mg (2 mL of 25 mg/5 mL syrup) once daily.
Elderly
Same as adults, with caution in patients with hepatic or renal impairment.
Renal_impairment
Reduced dose, e.g., 10 mg (2 mL) every other day for severe impairment.
How to Take
Take orally, with or without food.
Mechanism of Action
Unilor works by blocking histamine H1 receptors in the body, thereby reducing allergic symptoms.
Pharmacokinetics
Onset
Onset of action within 1-3 hours.
Excretion
Excreted in urine and feces.
Half life
Loratadine: 8-15 hours; active metabolite (descarboethoxyloratadine): 17-24 hours.
Absorption
Rapidly absorbed after oral administration.
Metabolism
Extensively metabolized in the liver to its active metabolite, descarboethoxyloratadine.
Side Effects
Contraindications
- Hypersensitivity to loratadine or any component of the formulation.
Drug Interactions
Cimetidine
May increase loratadine plasma concentrations, though usually not clinically significant.
Erythromycin
May increase loratadine plasma concentrations.
Ketoconazole
May increase loratadine plasma concentrations.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze.
Overdose
Symptoms of overdose may include somnolence, tachycardia, and headache. Treatment should be symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Not recommended during lactation as loratadine is excreted in breast milk.
Side Effects
Contraindications
- Hypersensitivity to loratadine or any component of the formulation.
Drug Interactions
Cimetidine
May increase loratadine plasma concentrations, though usually not clinically significant.
Erythromycin
May increase loratadine plasma concentrations.
Ketoconazole
May increase loratadine plasma concentrations.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze.
Overdose
Symptoms of overdose may include somnolence, tachycardia, and headache. Treatment should be symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Not recommended during lactation as loratadine is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved by major regulatory bodies (e.g., FDA)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Loratadine has undergone extensive clinical trials demonstrating its efficacy and safety for allergic conditions.
Lab Monitoring
- Usually not required for routine use. Liver function tests may be considered in patients with pre-existing hepatic impairment.
Doctor Notes
- Unilor is a second-generation antihistamine with a low potential for sedation.
- Dose adjustment may be necessary in patients with significant hepatic or renal impairment.
Patient Guidelines
- Take exactly as directed by your doctor or pharmacist.
- Do not exceed the recommended dose.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause drowsiness in some individuals, exercise caution when driving or operating machinery.
Lifestyle Advice
- Avoid alcohol consumption as it may enhance drowsiness.
- Stay hydrated to help alleviate dry mouth.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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