Utrobin
Generic Name
Utrobin 5 mg Tablet
Manufacturer
HealthCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| utrobin 5 mg tablet | ৳ 20.00 | ৳ 200.00 |
Description
Overview of the medicine
Utrobin 5 mg Tablet is used for various gynaecological conditions that require modulation of uterine activity or hormonal support. It helps in managing symptoms like dysmenorrhea and menorrhagia.
Uses & Indications
Dosage
Adults
One 5 mg tablet once daily for 3-6 months, or as directed by the physician.
Elderly
No specific dose adjustment is typically required, but caution is advised in patients with compromised hepatic or renal function.
Renal_impairment
Use with caution; dose adjustment may be necessary in severe renal impairment.
How to Take
Utrobin 5 mg Tablet should be taken orally with water, preferably at the same time each day. It can be taken with or without food.
Mechanism of Action
Utrobin is believed to exert its action by selectively binding to specific uterine receptors, leading to either relaxation or contraction of uterine muscles, depending on the physiological context. It may also influence local hormonal pathways.
Pharmacokinetics
Onset
Within 1-2 hours of administration.
Excretion
Mainly excreted via urine (60%) and feces (40%) as metabolites.
Half life
Approximately 8-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract after oral administration.
Metabolism
Primarily metabolized in the liver via CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients.
- Undiagnosed vaginal bleeding.
- Severe liver disease.
- Active thromboembolic disorders.
Drug Interactions
CYP3A4 Inducers (e.g., Rifampicin, Phenytoin)
May decrease plasma concentrations of Utrobin, reducing its efficacy.
CYP3A4 Inhibitors (e.g., Ketoconazole, Ritonavir)
May increase plasma concentrations of Utrobin, potentially increasing side effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive measures should be initiated. There is no specific antidote. Gastric lavage may be considered if ingestion is recent.
Pregnancy & Lactation
Utrobin is generally contraindicated during pregnancy. It is not recommended during lactation as it may be excreted in breast milk.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients.
- Undiagnosed vaginal bleeding.
- Severe liver disease.
- Active thromboembolic disorders.
Drug Interactions
CYP3A4 Inducers (e.g., Rifampicin, Phenytoin)
May decrease plasma concentrations of Utrobin, reducing its efficacy.
CYP3A4 Inhibitors (e.g., Ketoconazole, Ritonavir)
May increase plasma concentrations of Utrobin, potentially increasing side effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive measures should be initiated. There is no specific antidote. Gastric lavage may be considered if ingestion is recent.
Pregnancy & Lactation
Utrobin is generally contraindicated during pregnancy. It is not recommended during lactation as it may be excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Patented
Clinical Trials
Phase III clinical trials completed demonstrating efficacy and safety for dysmenorrhea and menorrhagia. Ongoing post-marketing surveillance.
Lab Monitoring
- Liver function tests (periodically during long-term therapy)
- Blood coagulation parameters (if risk factors for thrombosis are present)
Doctor Notes
- Advise patients about potential hormonal side effects.
- Monitor liver function periodically in patients on long-term therapy.
- Evaluate for underlying causes of abnormal uterine bleeding before initiating treatment.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not stop taking Utrobin without consulting your doctor, even if you feel better.
- Report any unusual or severe side effects to your healthcare provider immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Utrobin may cause dizziness in some individuals. If you experience dizziness, avoid driving or operating machinery.
Lifestyle Advice
- Maintain a healthy diet and regular exercise.
- Avoid smoking and excessive alcohol consumption.
- Practice stress management techniques.
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