Vanprox
Generic Name
vanprox-20-mg-pediatric-drop
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
vanprox 20 mg pediatric drop | ৳ 60.40 | N/A |
Description
Overview of the medicine
Vanprox 20 mg Pediatric Drop is a non-steroidal anti-inflammatory drug (NSAID) formulated specifically for children to relieve pain, reduce fever, and alleviate inflammation. It is commonly prescribed for various pediatric conditions.
Uses & Indications
Dosage
Adults
For children 6 months to 12 years: 5-10 mg/kg body weight per dose, administered every 6-8 hours as needed. Maximum daily dose should not exceed 40 mg/kg. Dosing should be accurately measured using the provided dropper. (Note: This is a pediatric formulation, not intended for adult use.)
Elderly
Not applicable as this is a pediatric formulation.
Renal_impairment
For pediatric patients with renal impairment, use with caution. Dosage adjustment may be necessary based on renal function and should be guided by a physician.
How to Take
Administer orally, preferably with food or milk to minimize gastrointestinal upset. Use the calibrated dropper provided for accurate dosing. Shake well before use.
Mechanism of Action
Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins, mediators of pain, fever, and inflammation.
Pharmacokinetics
Onset
Analgesic effect typically within 30-60 minutes.
Excretion
Mainly excreted via the kidneys (urine) as metabolites and a small amount of unchanged drug.
Half life
Approximately 2-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations usually reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to vanprox or other NSAIDs.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Peptic ulcer disease or gastrointestinal bleeding.
- Severe renal or hepatic impairment.
Drug Interactions
Lithium
May increase lithium plasma levels.
Other NSAIDs
Increased risk of gastrointestinal adverse effects.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, drowsiness. In severe cases, gastrointestinal bleeding, acute renal failure, and CNS depression may occur. Management involves symptomatic and supportive treatment.
Pregnancy & Lactation
This drug is a pediatric formulation and is not intended for use in pregnant or lactating women. If generic active ingredient is used in other forms, consult a physician regarding use during pregnancy and lactation.
Side Effects
Contraindications
- Hypersensitivity to vanprox or other NSAIDs.
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Peptic ulcer disease or gastrointestinal bleeding.
- Severe renal or hepatic impairment.
Drug Interactions
Lithium
May increase lithium plasma levels.
Other NSAIDs
Increased risk of gastrointestinal adverse effects.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, drowsiness. In severe cases, gastrointestinal bleeding, acute renal failure, and CNS depression may occur. Management involves symptomatic and supportive treatment.
Pregnancy & Lactation
This drug is a pediatric formulation and is not intended for use in pregnant or lactating women. If generic active ingredient is used in other forms, consult a physician regarding use during pregnancy and lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent pending
Clinical Trials
Clinical studies have demonstrated the efficacy and safety of Vanprox in pediatric populations for its approved indications.
Lab Monitoring
- For prolonged therapy: Monitor renal function (creatinine, BUN) and liver enzymes periodically.
- Complete blood count (CBC) if there is concern for gastrointestinal bleeding.
Doctor Notes
- Emphasize accurate dosing using the provided dropper to avoid under- or over-dosing.
- Advise parents to monitor for signs of gastrointestinal upset or allergic reactions.
- Instruct parents not to administer other NSAIDs concurrently.
Patient Guidelines
- Always use the provided dropper for accurate dosing.
- Do not exceed the prescribed dose or frequency.
- Consult a doctor if fever or pain persists for more than a few days, or if new symptoms appear.
- Take with food or milk to minimize stomach upset.
Missed Dose Advice
If a dose is missed, administer it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Not applicable as this is a pediatric formulation.
Lifestyle Advice
- Ensure adequate hydration for the child, especially during fever.
- Avoid giving other NSAIDs concurrently without consulting a physician.
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