Vinzam
Generic Name
Azithromycin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vinzam 200 mg suspension | ৳ 100.00 | N/A |
Description
Overview of the medicine
Vinzam 200 mg Suspension is an antibiotic medication containing Azithromycin. It belongs to the macrolide class of antibiotics and is used to treat a wide range of bacterial infections.
Uses & Indications
Dosage
Adults
Not typically used for adults in 200 mg/5 ml suspension formulation; adult dosage usually involves higher strength tablets. Consult physician.
Elderly
No specific dose adjustment is required for elderly patients with normal renal and hepatic function.
Renal_impairment
No dose adjustment is necessary for mild to moderate renal impairment. Caution is advised in severe renal impairment (creatinine clearance <10 mL/min).
How to Take
Vinzam 200 mg Suspension should be taken orally, with or without food. Shake the bottle well before each use. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
Azithromycin works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit of susceptible bacteria, thereby interfering with the translation of mRNA and preventing bacterial growth.
Pharmacokinetics
Onset
Clinical effects are typically observed within hours of administration.
Excretion
Primarily excreted unchanged in the bile. A small amount is excreted via the kidneys.
Half life
The terminal elimination half-life is approximately 2 to 4 days.
Absorption
Rapidly absorbed after oral administration; bioavailability is approximately 37%. Peak plasma concentrations occur 2-3 hours post-dose.
Metabolism
Partially metabolized in the liver by N-demethylation, but the majority is excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic, or to any component of the formulation.
- •History of cholestatic jaundice or hepatic dysfunction associated with prior azithromycin use.
Drug Interactions
Warfarin
Increased anticoagulant effect, monitor INR.
Nelfinavir
Increased azithromycin serum concentrations; monitor for side effects.
Ergot derivatives (e.g., Ergotamine)
Potential for acute ergot toxicity, avoid concomitant use.
Antacids (containing aluminum or magnesium)
Decreased peak plasma concentrations of azithromycin; take azithromycin at least 2 hours before or after antacids.
Storage
Store the dry powder below 30°C, protected from light and moisture. Keep out of reach of children. Store reconstituted suspension as per shelf life guidelines.
Overdose
Symptoms of overdose may include nausea, vomiting, diarrhea, abdominal discomfort, and reversible hearing loss. Treatment should be symptomatic and supportive, including gastric lavage and general supportive measures.
Pregnancy & Lactation
Pregnancy Category B. Azithromycin should be used during pregnancy only if clearly needed. It is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Unreconstituted powder: 24-36 months. Reconstituted suspension: 5 days at room temperature (below 30°C) or 10 days refrigerated (2-8°C).
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory bodies
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
