Vitaplex
Generic Name
Multivitamin B-complex Syrup
Manufacturer
Popular Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vitaplex 5 mg syrup | ৳ 25.00 | N/A |
Description
Overview of the medicine
Vitaplex 5 mg Syrup is a multivitamin B-complex preparation designed to supplement essential B vitamins. It aids in various metabolic functions, energy production, and nerve health. Primarily used to treat or prevent vitamin B deficiencies.
Uses & Indications
Dosage
Adults
Adults: 1-2 teaspoonfuls (5-10 ml) 2-3 times daily, or as directed by a physician.
Elderly
Elderly: Same as adult dosage, no specific adjustment usually required unless severe renal impairment is present for specific components.
Renal_impairment
No specific dosage adjustment is typically required for a general multivitamin B-complex. Consult a physician for high-dose formulations or severe impairment.
How to Take
Take orally, with or without food. It can be mixed with water or fruit juice if desired. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
B vitamins act as coenzymes in numerous metabolic pathways, including carbohydrate, fat, and protein metabolism, facilitating energy production and cellular functions. For example, Thiamine (B1) is crucial for carbohydrate metabolism, Riboflavin (B2) for energy production and cellular growth, Pyridoxine (B6) for amino acid metabolism and neurotransmitter synthesis, Niacinamide (B3) for cellular respiration, and Pantothenic acid (B5) for fatty acid synthesis.
Pharmacokinetics
Onset
Effects on metabolic processes can begin shortly after absorption, but symptomatic improvement in deficiency states may take days to weeks.
Excretion
Primarily excreted unchanged or as metabolites in the urine. Renal clearance is the main route of elimination for most water-soluble B vitamins.
Half life
Varies significantly for each B vitamin; generally, they are water-soluble and not stored in large quantities, leading to relatively short half-lives (hours to days) and rapid excretion.
Absorption
Readily absorbed from the gastrointestinal tract, primarily in the small intestine. Absorption rates can vary depending on the specific vitamin and presence of other food components.
Metabolism
B vitamins are metabolized in the liver and various tissues to their active coenzyme forms. Excess amounts are typically not extensively metabolized.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- Leber's disease or other optic neuropathies (due to Vitamin B12, if present in combination, as it can exacerbate the condition).
Drug Interactions
Levodopa
High doses of Pyridoxine (Vitamin B6) may reduce the effectiveness of Levodopa (used in Parkinson's disease). This interaction is less significant with Carbidopa/Levodopa combinations.
Isoniazid
Can interfere with Pyridoxine metabolism, potentially requiring increased B6 supplementation.
Certain antibiotics (e.g., Cycloserine)
May increase the requirement for Pyridoxine.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Overdose
Overdose is rare with water-soluble vitamins as excess amounts are usually excreted. However, extremely high doses of certain B vitamins (especially B6) over a long period can lead to neuropathy. Symptoms might include tingling, numbness, and nerve damage. Treatment is generally supportive and involves discontinuing the product.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when taken within recommended daily allowances. Consult a physician for specific dosage and suitability during these periods.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation.
- Leber's disease or other optic neuropathies (due to Vitamin B12, if present in combination, as it can exacerbate the condition).
Drug Interactions
Levodopa
High doses of Pyridoxine (Vitamin B6) may reduce the effectiveness of Levodopa (used in Parkinson's disease). This interaction is less significant with Carbidopa/Levodopa combinations.
Isoniazid
Can interfere with Pyridoxine metabolism, potentially requiring increased B6 supplementation.
Certain antibiotics (e.g., Cycloserine)
May increase the requirement for Pyridoxine.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze. Keep the bottle tightly closed.
Overdose
Overdose is rare with water-soluble vitamins as excess amounts are usually excreted. However, extremely high doses of certain B vitamins (especially B6) over a long period can lead to neuropathy. Symptoms might include tingling, numbness, and nerve damage. Treatment is generally supportive and involves discontinuing the product.
Pregnancy & Lactation
Generally considered safe during pregnancy and lactation when taken within recommended daily allowances. Consult a physician for specific dosage and suitability during these periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Usually 24 to 36 months from the date of manufacture when stored under recommended conditions. Refer to the product label for exact expiry date.
Availability
Available in pharmacies, drugstores, and some supermarkets
Approval Status
Approved by local regulatory authorities (e.g., DGDA) for over-the-counter use
Patent Status
Off-patent, widely available as generic
Clinical Trials
For general multivitamin B-complex supplements, extensive specific clinical trials are less common as their efficacy in preventing and treating deficiencies is well-established. Studies may focus on specific B vitamin formulations or their impact on particular health conditions.
Lab Monitoring
- Routine lab monitoring is not typically required for individuals taking multivitamin B-complex preparations for general supplementation. In cases of diagnosed deficiency, specific vitamin levels may be monitored.
Doctor Notes
- Educate patients on the importance of a balanced diet even with supplementation.
- Advise patients to report any unusual side effects or symptoms.
- Emphasize that this is a supplement and not a replacement for medical treatment of underlying conditions.
Patient Guidelines
- Take as directed by your physician or pharmacist, or follow instructions on the product label.
- Do not exceed the recommended daily dose.
- Store the syrup properly to maintain its efficacy.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Vitaplex 5 mg Syrup is generally not expected to impair the ability to drive or operate machinery.
Lifestyle Advice
- While taking multivitamin B-complex, maintain a balanced diet rich in fruits, vegetables, and whole grains to ensure comprehensive nutrient intake.
- Regular physical activity can complement the benefits of vitamin supplementation.
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