xenoderm
Generic Name
Xenoderm 0.05%
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xenoderm 05 mg ointment | ৳ 150.00 | N/A |
Description
Overview of the medicine
Xenoderm 0.05% Ointment is a potent topical corticosteroid used for the treatment of various inflammatory and pruritic skin conditions.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected area once or twice daily. Do not use for more than 2-4 weeks without medical review.
Elderly
No specific dosage adjustment required; however, use with caution due to thinner skin.
Renal_impairment
No specific dosage adjustment required for topical application.
How to Take
For external use only. Apply a thin layer of ointment to the affected skin area and gently rub in. Do not apply to open wounds, eyes, or mucous membranes. Wash hands before and after application.
Mechanism of Action
Xenoderm 0.05% Ointment exerts its effects by inducing phospholipase A2 inhibitory proteins, called lipocortins. These proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.
Pharmacokinetics
Onset
Effects typically observed within a few hours to days of application.
Excretion
Excreted mainly via urine, and to a lesser extent, bile, after systemic absorption.
Half life
Not well-defined for topical application due to minimal systemic absorption.
Absorption
Limited systemic absorption after topical application; however, absorption can increase with occlusive dressings, prolonged use, or application to large surface areas.
Metabolism
Metabolized primarily in the liver, similar to other corticosteroids, once absorbed systemically.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients.
- Untreated cutaneous bacterial, fungal, or viral infections.
- Rosacea, acne vulgaris, perioral dermatitis.
- Pruritus without inflammation.
- Children under 1 year of age.
Drug Interactions
Other Topical Products
Avoid concomitant use on the same area unless advised by a doctor to prevent altered absorption or efficacy.
Systemic Corticosteroids
Increased risk of systemic side effects if absorbed significantly.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. However, prolonged or excessive use may lead to systemic effects such as Cushing's syndrome, adrenal suppression. Symptomatic treatment is recommended.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients.
- Untreated cutaneous bacterial, fungal, or viral infections.
- Rosacea, acne vulgaris, perioral dermatitis.
- Pruritus without inflammation.
- Children under 1 year of age.
Drug Interactions
Other Topical Products
Avoid concomitant use on the same area unless advised by a doctor to prevent altered absorption or efficacy.
Systemic Corticosteroids
Increased risk of systemic side effects if absorbed significantly.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is unlikely with topical use. However, prolonged or excessive use may lead to systemic effects such as Cushing's syndrome, adrenal suppression. Symptomatic treatment is recommended.
Pregnancy & Lactation
Use during pregnancy and lactation should only be considered if the potential benefit outweighs the potential risk to the fetus or infant. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA, Bangladesh
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical data supports the efficacy and safety of topical corticosteroids for indicated conditions. Specific trials for Xenoderm 0.05% Ointment demonstrated comparable effectiveness and tolerability.
Lab Monitoring
- Not typically required for localized topical application. If extensive systemic absorption is suspected, monitoring of adrenal function may be considered.
Doctor Notes
- Advise patients on appropriate application technique and duration of use.
- Monitor for signs of local skin reactions or systemic absorption, especially in children and with prolonged use.
- Consider step-down therapy or alternatives for chronic conditions.
Patient Guidelines
- Apply sparingly to the affected area.
- Avoid contact with eyes.
- Do not use for longer than prescribed.
- Avoid occlusive dressings unless specifically instructed by your doctor.
- Inform your doctor about all other medications you are using.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Xenoderm 0.05% Ointment is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene.
- Avoid known irritants or allergens.
- Keep skin moisturized to prevent dryness.
- Protect skin from excessive sun exposure.
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Global Brand Names
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