Xiamin
Generic Name
IncobotulinumtoxinA
Manufacturer
Merz Pharmaceuticals
Country
Germany
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xiamin 750 mg tablet | ৳ 15.00 | ৳ 90.00 |
Description
Overview of the medicine
Xiamin (IncobotulinumtoxinA) is a neurotoxin used to temporarily improve the appearance of moderate to severe glabellar lines, treat cervical dystonia, blepharospasm, and spasticity.
Uses & Indications
Dosage
Adults
Varies by indication, typically 20-300 units per treatment site.
Elderly
Similar to adults, with caution.
Renal_impairment
No specific dose adjustment needed.
How to Take
Intramuscular injection by a trained physician.
Mechanism of Action
Blocks acetylcholine release at the neuromuscular junction, causing muscle paralysis.
Pharmacokinetics
Onset
Within 2-3 days, full effect in 1-2 weeks.
Excretion
Inactive components are eliminated.
Half life
Unknown, effect lasts for 3-6 months.
Absorption
Minimal systemic absorption after intramuscular injection.
Metabolism
Metabolized by proteases.
Side Effects
Contraindications
- Hypersensitivity to botulinum toxin or albumin
- Infection at the proposed injection site
Drug Interactions
Aminoglycoside antibiotics
May potentiate the effects of botulinum toxin.
Curare-like non-depolarizing blockers
May potentiate the effects.
Storage
Store unopened vials at room temperature (below 25°C) or refrigerated (2-8°C). Reconstituted solution must be used within 24 hours.
Overdose
Symptoms of systemic weakness, respiratory distress. Supportive care, mechanical ventilation may be required.
Pregnancy & Lactation
Use only if potential benefit outweighs risk. Category C.
Side Effects
Contraindications
- Hypersensitivity to botulinum toxin or albumin
- Infection at the proposed injection site
Drug Interactions
Aminoglycoside antibiotics
May potentiate the effects of botulinum toxin.
Curare-like non-depolarizing blockers
May potentiate the effects.
Storage
Store unopened vials at room temperature (below 25°C) or refrigerated (2-8°C). Reconstituted solution must be used within 24 hours.
Overdose
Symptoms of systemic weakness, respiratory distress. Supportive care, mechanical ventilation may be required.
Pregnancy & Lactation
Use only if potential benefit outweighs risk. Category C.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Specific to manufacturer, typically 36 months when unopened.
Availability
Hospitals, Specialized clinics
Approval Status
FDA Approved
Patent Status
Patented by Merz Pharmaceuticals
Clinical Trials
Extensive clinical trials support its efficacy and safety for approved indications.
Lab Monitoring
- Not typically required for routine use.
Doctor Notes
- Administer only by trained professionals.
- Proper dosing and injection technique are crucial to prevent spread of toxin.
Patient Guidelines
- Report any muscle weakness or breathing difficulties.
- Avoid rubbing the injection site immediately after treatment.
- Do not receive Xiamin if you have an infection at the injection site.
Missed Dose Advice
Not applicable as it is a single administration product in clinical settings.
Driving Precautions
May cause temporary visual disturbances or muscle weakness; use caution.
Lifestyle Advice
- Maintain good posture, follow physician's instructions.
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