Zigrow B
Generic Name
Vitamin B Complex (Thiamine, Riboflavin, Pyridoxine, Nicotinamide, Calcium Pantothenate)
Manufacturer
XYZ Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| zigrow b syrup | ৳ 60.00 | N/A |
| zigrow b tablet | ৳ 3.50 | N/A |
Description
Overview of the medicine
Zigrow B is a vitamin B complex supplement used to prevent and treat deficiencies of B vitamins. These vitamins play crucial roles in cellular metabolism, energy production, nerve function, and red blood cell formation.
Uses & Indications
Dosage
Adults
Typically 1-2 tablets daily, or as directed by a physician.
Elderly
Dosage usually remains the same as for adults, unless specific deficiencies or conditions warrant adjustment. Consult a physician.
Renal_impairment
No specific dose adjustment is usually required for mild to moderate renal impairment, but caution is advised in severe cases. Consult a physician.
How to Take
Take orally with water, with or without food. Follow the physician's or pharmacist's instructions.
Mechanism of Action
Each B vitamin acts as a coenzyme in various metabolic processes. For example, Thiamine (B1) is essential for carbohydrate metabolism, Riboflavin (B2) for energy production, Pyridoxine (B6) for amino acid metabolism and neurotransmitter synthesis, Nicotinamide (B3) for cellular respiration, and Calcium Pantothenate (B5) for coenzyme A synthesis.
Pharmacokinetics
Onset
Onset of action is gradual, as the body utilizes the vitamins to correct deficiencies and support metabolic processes. Symptomatic improvement may be noticed within days to weeks depending on the severity of deficiency.
Excretion
Primarily excreted unchanged or as metabolites in the urine, due to their water-soluble nature. Minimal storage occurs in the body.
Half life
Half-life varies for each individual B vitamin, generally ranging from a few hours to several days due to their water-soluble nature and rapid excretion.
Absorption
Water-soluble B vitamins are readily absorbed from the gastrointestinal tract, primarily in the small intestine.
Metabolism
Many B vitamins are converted to their active coenzyme forms in the liver and other tissues, where they participate in various metabolic pathways.
Side Effects
Contraindications
- Known hypersensitivity to any component of the vitamin B complex.
Drug Interactions
Alcohol
Chronic alcohol consumption can impair B vitamin absorption and metabolism.
Antacids
Some antacids may decrease the absorption of B vitamins.
Levodopa
Pyridoxine (B6) may reduce the effectiveness of levodopa (used for Parkinson's disease).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose with water-soluble vitamins like B complex is rare because excess amounts are typically excreted in the urine. However, extremely high doses of individual B vitamins (e.g., Pyridoxine) can lead to adverse effects like peripheral neuropathy. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased nutritional demands. However, always consult a doctor before taking any medication or supplement during these periods.
Side Effects
Contraindications
- Known hypersensitivity to any component of the vitamin B complex.
Drug Interactions
Alcohol
Chronic alcohol consumption can impair B vitamin absorption and metabolism.
Antacids
Some antacids may decrease the absorption of B vitamins.
Levodopa
Pyridoxine (B6) may reduce the effectiveness of levodopa (used for Parkinson's disease).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose with water-soluble vitamins like B complex is rare because excess amounts are typically excreted in the urine. However, extremely high doses of individual B vitamins (e.g., Pyridoxine) can lead to adverse effects like peripheral neuropathy. Symptomatic and supportive treatment is recommended.
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation to meet increased nutritional demands. However, always consult a doctor before taking any medication or supplement during these periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Generally 2-3 years from the date of manufacture, refer to the package for exact expiry date.
Availability
Available in all pharmacies and drug stores nationwide
Approval Status
Approved (OTC)
Patent Status
Off-patent (Generic)
WHO Essential Medicine
YesClinical Trials
As a well-established vitamin supplement, Zigrow B does not typically undergo new clinical trials for its primary indications. Its efficacy and safety are widely known.
Doctor Notes
- Advise patients on the importance of a balanced diet alongside supplementation.
- Consider B complex for patients with malabsorption syndromes, chronic alcoholics, or those on certain medications that deplete B vitamins.
- Monitor for signs of deficiency and adjust dosage as needed.
Patient Guidelines
- Take the medicine as directed by your healthcare provider or package instructions.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications and supplements you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Zigrow B is not known to impair the ability to drive or operate machinery. However, if you experience any side effects that affect your concentration or coordination, avoid these activities.
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