Zocort
Generic Name
Betamethasone
Manufacturer
Fictional Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
zocort 1 cream | ৳ 70.00 | N/A |
Description
Overview of the medicine
Zocort contains Betamethasone, a potent synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is used to treat a wide range of inflammatory and autoimmune conditions.
Uses & Indications
Dosage
Adults
Initial dose 0.5 mg to 5 mg daily, adjusted according to response. Usually given once daily.
Elderly
Lower initial doses may be required; caution due to increased risk of side effects.
Renal_impairment
No specific dosage adjustment required; monitor for fluid retention.
How to Take
Take orally with food to minimize gastrointestinal upset. Do not stop abruptly.
Mechanism of Action
Betamethasone acts by binding to intracellular glucocorticoid receptors, modifying gene expression to inhibit inflammatory mediators and suppress immune responses.
Pharmacokinetics
Onset
Rapid, within hours for anti-inflammatory effects.
Excretion
Mainly renal, as inactive metabolites.
Half life
Plasma half-life: 3-5 hours; biological half-life: 36-54 hours.
Absorption
Well absorbed from the gastrointestinal tract.
Metabolism
Primarily hepatic, metabolized by CYP3A4.
Side Effects
Contraindications
- Systemic fungal infections
- Untreated infections
- Hypersensitivity to betamethasone or other corticosteroids
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding.
Diuretics
Increased potassium loss.
Anticoagulants
May alter anticoagulant effects.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Acute overdose is rare. Chronic overdose can lead to Cushingoid features, adrenal suppression. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use during pregnancy only if potential benefit outweighs risk. Excreted in breast milk, consult doctor.
Side Effects
Contraindications
- Systemic fungal infections
- Untreated infections
- Hypersensitivity to betamethasone or other corticosteroids
Drug Interactions
NSAIDs
Increased risk of gastrointestinal bleeding.
Diuretics
Increased potassium loss.
Anticoagulants
May alter anticoagulant effects.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Acute overdose is rare. Chronic overdose can lead to Cushingoid features, adrenal suppression. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use during pregnancy only if potential benefit outweighs risk. Excreted in breast milk, consult doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensively studied in various inflammatory and autoimmune conditions, demonstrating efficacy.
Lab Monitoring
- Blood glucose
- Electrolyte levels
- Bone density (for long-term use)
- Blood pressure
Doctor Notes
- Always taper the dose gradually when discontinuing.
- Monitor for signs of infection, especially in immunocompromised patients.
- Consider calcium and vitamin D supplementation for long-term users.
Patient Guidelines
- Do not stop taking this medicine suddenly without consulting your doctor.
- Inform your doctor about any new symptoms or infections.
- Avoid contact with people who have infections like chickenpox or measles.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
Generally no effect on driving, but if you experience dizziness or visual disturbances, avoid driving.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D.
- Regular exercise to maintain bone health.
- Limit sodium intake.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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