Act
Generic Name
Paracetamol (Acetaminophen)
Manufacturer
Reputable Pharmaceutical Co. Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| act 120 mg suspension | ৳ 35.00 | N/A |
Description
Overview of the medicine
Act 120 mg Suspension is an antipyretic and analgesic medication containing Paracetamol, used to relieve mild to moderate pain and reduce fever in children.
Uses & Indications
Dosage
Adults
This 120 mg/5ml suspension is primarily for pediatric use. Adults typically use higher doses/forms (e.g., 500mg tablets).
Elderly
Not specifically formulated for elderly, who would typically use adult formulations.
Renal_impairment
Use with caution. Dosage reduction may be required in severe renal dysfunction. Consult a healthcare professional.
How to Take
Administer orally. Shake the bottle well before use. Use a measuring spoon or oral syringe for accurate dosing.
Mechanism of Action
Paracetamol is thought to act primarily by inhibiting prostaglandin synthesis in the central nervous system, thereby exerting its analgesic and antipyretic effects. It has weak anti-inflammatory effects.
Pharmacokinetics
Onset
30-60 minutes for analgesic/antipyretic effect.
Excretion
Excreted mainly in the urine as glucuronide and sulfate conjugates. Less than 5% is excreted unchanged.
Half life
1.5-3 hours in adults, slightly longer in neonates.
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 30-60 minutes.
Metabolism
Primarily metabolized in the liver via glucuronidation and sulfation. A small portion is metabolized by cytochrome P450 to a toxic intermediate (NAPQI), which is detoxified by glutathione.
Side Effects
Contraindications
- •Known hypersensitivity to Paracetamol or any other component of the formulation.
- •Severe hepatic impairment.
Drug Interactions
Warfarin
May increase the anticoagulant effect of warfarin, increasing the risk of bleeding.
Cholestyramine
Reduces paracetamol absorption if given within 1 hour.
Carbamazepine, Phenobarbital, Phenytoin
May increase the risk of hepatotoxicity with paracetamol.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Do not freeze.
Overdose
Symptoms include nausea, vomiting, abdominal pain, and liver damage. Seek immediate medical attention. Treatment involves gastric lavage, activated charcoal, and administration of N-acetylcysteine.
Pregnancy & Lactation
Considered safe for use during pregnancy and lactation at recommended doses, but consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture. Once opened, use within 28 days.
Availability
Pharmacies, hospitals, supermarkets
Approval Status
Approved by FDA/DGDA
Patent Status
Generic, off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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