Bactazim
Generic Name
Cefixime
Manufacturer
ACME Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bactazim 200 mg capsule | ৳ 35.00 | ৳ 140.00 |
Description
Overview of the medicine
Cefixime is a broad-spectrum, third-generation cephalosporin antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
200-400 mg once or twice daily, depending on the severity of the infection. For uncomplicated gonorrhea, a single 400 mg dose.
Elderly
No specific dosage adjustment required unless renal impairment is present.
Renal_impairment
Dosage adjustment is necessary for patients with creatinine clearance <60 mL/min.
How to Take
Bactazim 200 mg Capsule can be taken orally, with or without food. It is recommended to take it at the same time each day.
Mechanism of Action
It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and bacterial death.
Pharmacokinetics
Onset
Rapid.
Excretion
Primarily via renal excretion (about 50% unchanged in urine) and also via biliary excretion.
Half life
3-4 hours.
Absorption
Approximately 40-50% orally absorbed, absorption is not significantly affected by food.
Metabolism
Not extensively metabolized in the body.
Side Effects
Contraindications
- Known hypersensitivity to cefixime or any other cephalosporin antibiotics.
- History of anaphylaxis to penicillin antibiotics.
Drug Interactions
Nifedipine
May increase cefixime absorption.
Carbamazepine
Concomitant use may result in increased carbamazepine plasma levels.
Warfarin and other anticoagulants
May increase prothrombin time (INR) and the risk of bleeding. Close monitoring is advised.
Storage
Store in a cool and dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote exists. Gastric lavage may be indicated. Hemodialysis and peritoneal dialysis do not effectively remove cefixime from the body. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Cefixime should be used during pregnancy only if clearly needed. Use with caution in nursing mothers; consult a doctor.
Side Effects
Contraindications
- Known hypersensitivity to cefixime or any other cephalosporin antibiotics.
- History of anaphylaxis to penicillin antibiotics.
Drug Interactions
Nifedipine
May increase cefixime absorption.
Carbamazepine
Concomitant use may result in increased carbamazepine plasma levels.
Warfarin and other anticoagulants
May increase prothrombin time (INR) and the risk of bleeding. Close monitoring is advised.
Storage
Store in a cool and dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
No specific antidote exists. Gastric lavage may be indicated. Hemodialysis and peritoneal dialysis do not effectively remove cefixime from the body. Management is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category B. Cefixime should be used during pregnancy only if clearly needed. Use with caution in nursing mothers; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
DGDA Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Cefixime has undergone extensive clinical trials demonstrating its efficacy and safety across various bacterial infections.
Lab Monitoring
- Periodic assessment of renal and hepatic function during prolonged therapy.
- Monitor prothrombin time/INR if co-administered with anticoagulants.
Doctor Notes
- Emphasize the importance of completing the full course of antibiotics, even if the patient feels better, to prevent bacterial resistance.
- Advise patients on potential side effects, particularly gastrointestinal disturbances, and when to seek medical attention.
Patient Guidelines
- Complete the entire prescribed course of medication, even if symptoms improve.
- Do not share this medication with others.
- Contact your doctor if symptoms do not improve or worsen.
- Report any severe or persistent side effects to your healthcare provider.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness in some individuals. Patients should be cautious when driving or operating machinery until they know how cefixime affects them.
Lifestyle Advice
- Maintain adequate hydration.
- Avoid alcohol if experiencing dizziness or other CNS side effects.
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