For external use only. Apply a thin layer to the affected area and rub in gently. Wash hands before and after application. Avoid contact with eyes and mucous membranes. Do not use under occlusive dressings unless advised by a doctor.

Betamethasone, a potent corticosteroid, acts by inducing phospholipase A2 inhibitory proteins (lipocortins), thereby inhibiting the release of arachidonic acid. This leads to the suppression of various inflammatory mediators like prostaglandins and leukotrienes. Neomycin, an aminoglycoside antibiotic, binds to the 30S ribosomal subunit of susceptible bacteria, thereby inhibiting bacterial protein synthesis and leading to bacterial cell death.

• •Hypersensitivity to Betamethasone, Neomycin, or any component of the cream
• •Viral skin infections (e.g., herpes simplex, varicella)
• •Fungal skin infections
• •Tuberculosis of the skin
• •Acne rosacea
• •Perioral dermatitis
• •Ulcerative conditions
• •Vaccination reactions

Store below 30°C in a cool, dry place. Protect from light and moisture. Do not freeze. Keep out of reach of children.

Topical overdose is unlikely to cause acute systemic effects. Chronic overdose or misuse can lead to local skin atrophy, striae, telangiectasias, or systemic corticosteroid effects (e.g., Cushing's syndrome) and, rarely, neomycin systemic toxicity if applied to large areas of broken skin.

Use during pregnancy only if the potential benefit justifies the potential risk to the fetus, and preferably avoid during the first trimester. For lactation, use with caution; minimal systemic absorption suggests low risk, but avoid applying to breasts.