Colipan
Generic Name
Phloroglucinol 20 mg tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| colipan 20 mg tablet | ৳ 5.65 | N/A |
Description
Overview of the medicine
Phloroglucinol is an antispasmodic agent used for symptomatic treatment of pain associated with functional disorders of the gastrointestinal tract and biliary system. Also used in urological and gynecological spasms.
Uses & Indications
Dosage
Adults
Usually 20-40 mg, 2-3 times daily, as directed by physician.
Elderly
No specific dose adjustment generally required, but caution is advised.
Renal_impairment
No specific dose adjustment recommended, but use with caution.
How to Take
Oral. Swallow the tablet whole with water. Can be taken with or without food.
Mechanism of Action
Phloroglucinol acts directly on the smooth muscles of the digestive, biliary, urinary, and uterine tracts, reducing spasms without disrupting normal peristalsis. It works by inhibiting the synthesis of prostaglandins and other inflammatory mediators, thereby relieving pain and spasm.
Pharmacokinetics
Onset
Rapid onset of action, typically within 15-20 minutes.
Excretion
Primarily excreted via urine and bile as metabolites.
Half life
Short plasma half-life, approximately 1-2 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 15-20 minutes.
Metabolism
Extensively metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to phloroglucinol or any component of the formulation.
- •Intestinal obstruction.
- •Paralytic ileus.
Drug Interactions
Opioid analgesics
May antagonize the antispasmodic effect of phloroglucinol.
Other antispasmodics
Concurrent use may potentiate effects.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose are generally mild and may include gastrointestinal disturbances. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy: Use with caution, only if clearly needed and advised by a doctor. Studies in animals have not shown teratogenic effects, but human data is limited. Lactation: Not recommended during breastfeeding as it is unknown if phloroglucinol is excreted in human milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Generic drug
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Global Brand Names
International brand names for this medicine
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