Comfy
Generic Name
Comfy-2-mg-tablet
Manufacturer
MediCare Pharma Ltd. (Hypothetical)
Country
Bangladesh (Hypothetical)
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| comfy 2 mg tablet | ৳ 12.00 | ৳ 120.00 |
Description
Overview of the medicine
Comfy 2 mg Tablet is a medication used to treat anxiety disorders, insomnia, and certain seizure disorders. It acts on the central nervous system to produce a calming effect.
Uses & Indications
Dosage
Adults
Typical initial dose is 0.5-2 mg two or three times daily, adjusted according to response. Maximum recommended dose usually 10 mg/day.
Elderly
Initial dose should be lower, typically 0.5 mg once or twice daily, increasing cautiously.
Renal_impairment
Use with caution; dose reduction may be necessary. Start with lower doses.
How to Take
Take orally with or without food. Do not crush or chew the tablet. Swallow whole with water.
Mechanism of Action
Comfy 2 mg Tablet is thought to enhance the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity. This results in reduced neuronal excitability, leading to anxiolytic, sedative, hypnotic, and muscle relaxant properties.
Pharmacokinetics
Onset
Within 30-60 minutes for anxiolytic effects.
Excretion
Excreted mainly in the urine as inactive metabolites.
Half life
Approximately 10-20 hours (variable).
Absorption
Rapidly and well absorbed after oral administration. Peak plasma concentrations are usually reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily via glucuronidation, to inactive metabolites.
Side Effects
Contraindications
- •Acute narrow-angle glaucoma
- •Severe respiratory insufficiency
- •Severe hepatic insufficiency
- •Myasthenia gravis
- •Sleep apnea syndrome
Drug Interactions
Alcohol
Additive CNS depressant effects.
Opioids
Increased risk of sedation, respiratory depression, coma, and death.
Antihistamines (sedating)
Increased sedation.
Antifungals (e.g., ketoconazole)
May inhibit metabolism, increasing plasma levels.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include somnolence, confusion, diminished reflexes, and coma. Management involves supportive care, maintaining a patent airway, and if necessary, intravenous flumazenil (a benzodiazepine receptor antagonist) under close medical supervision.
Pregnancy & Lactation
Pregnancy Category D. May cause fetal harm. Avoid during pregnancy. Small amounts may pass into breast milk; not recommended during breastfeeding due to potential for sedation in the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Pharmacies, Hospitals
Approval Status
Approved (Hypothetical)
Patent Status
Expired (Hypothetical)
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Global Brand Names
International brand names for this medicine
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