D-Shine
Generic Name
Cholecalciferol (Vitamin D3)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| d shine 40000 iu capsule | ৳ 34.00 | ৳ 340.00 |
Description
Overview of the medicine
D-Shine 40,000 IU Capsule is a vitamin D3 supplement essential for calcium and phosphate absorption and bone health.
Uses & Indications
Dosage
Adults
Typically once weekly for vitamin D deficiency, or as directed by physician.
Elderly
Similar to adults, but vitamin D levels should be monitored.
Renal_impairment
Caution, monitor vitamin D levels; may require activated forms of Vitamin D.
How to Take
The medicine should be taken orally, preferably with the largest meal of the day to aid absorption.
Mechanism of Action
It regulates calcium and phosphate homeostasis in the body and aids in bone mineralization.
Pharmacokinetics
Onset
Several days to weeks for therapeutic effect.
Excretion
Excreted via bile and feces.
Half life
Parent compound ~15-20 hours; active metabolite (calcitriol) ~3-5 days.
Absorption
Well absorbed from the small intestine in the presence of bile salts.
Metabolism
Metabolized in the liver (25-hydroxylation to calcidiol) and kidney (1-alpha-hydroxylation to calcitriol).
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Hypervitaminosis D (excessive vitamin D levels)
- Severe malabsorption syndrome
Drug Interactions
Corticosteroids
May reduce vitamin D effects.
Cardiac glycosides
Increased risk of arrhythmia with hypercalcemia.
Thiazide diuretics
Increased risk of hypercalcemia.
Phenytoin/Barbiturates
May increase vitamin D metabolism.
Cholestyramine/Orlistat
May reduce vitamin D absorption.
Storage
Store below 30°C. Protect from light and moisture.
Overdose
Symptoms: hypercalcemia (nausea, vomiting, weakness, polyuria), renal impairment. Management: discontinue, low calcium diet, hydration.
Pregnancy & Lactation
Should be taken with physician's advice during pregnancy and lactation. High doses require caution.
Side Effects
Contraindications
- Hypercalcemia (high calcium levels in blood)
- Hypervitaminosis D (excessive vitamin D levels)
- Severe malabsorption syndrome
Drug Interactions
Corticosteroids
May reduce vitamin D effects.
Cardiac glycosides
Increased risk of arrhythmia with hypercalcemia.
Thiazide diuretics
Increased risk of hypercalcemia.
Phenytoin/Barbiturates
May increase vitamin D metabolism.
Cholestyramine/Orlistat
May reduce vitamin D absorption.
Storage
Store below 30°C. Protect from light and moisture.
Overdose
Symptoms: hypercalcemia (nausea, vomiting, weakness, polyuria), renal impairment. Management: discontinue, low calcium diet, hydration.
Pregnancy & Lactation
Should be taken with physician's advice during pregnancy and lactation. High doses require caution.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years
Availability
Available in pharmacies and drug stores
Approval Status
Generally Approved
Patent Status
Generic
Clinical Trials
Numerous clinical trials confirm the efficacy and safety of vitamin D for deficiency and bone health.
Lab Monitoring
- Serum 25(OH)D levels
- Serum calcium
- Phosphate
- Parathyroid hormone
Doctor Notes
- Inform patients about symptoms of hypercalcemia.
- Regular monitoring of vitamin D and calcium levels is advisable.
Patient Guidelines
- Take as directed by your physician.
- Do not exceed the prescribed dose.
- Inform your doctor about all your medications.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. Do not double dose to compensate for a missed one.
Driving Precautions
No known adverse effects on driving or operating machinery.
Lifestyle Advice
- Maintain a balanced diet.
- Get moderate sun exposure regularly.
- Engage in regular exercise.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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