Daprosis
Generic Name
Daprosis
Manufacturer
PharmaCo Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| daprosis 2 mg tablet | ৳ 100.00 | ৳ 700.00 |
Description
Overview of the medicine
Daprosis 2 mg tablet is a corticosteroid used to treat various inflammatory and autoimmune conditions. It works by suppressing the body's immune response and reducing inflammation.
Uses & Indications
Dosage
Adults
Initial dose typically 1-2 mg orally once daily, adjusted based on response and tolerability. Max daily dose 10 mg.
Elderly
Start with lower doses and titrate carefully due to increased susceptibility to side effects.
Renal_impairment
No specific dose adjustment generally required, but caution is advised in severe cases.
How to Take
Take orally, preferably with food or milk to minimize gastrointestinal upset.
Mechanism of Action
Daprosis binds to glucocorticoid receptors, modulating gene expression to produce anti-inflammatory and immunosuppressive effects.
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Excreted mainly via kidneys.
Half life
Approximately 3-4 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Metabolism
Primarily hepatic metabolism.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to Daprosis or any component of the formulation
- Live or live-attenuated vaccines during immunosuppressive doses
Drug Interactions
NSAIDs
Increased risk of gastrointestinal ulceration and bleeding.
Warfarin
May enhance or diminish anticoagulant effects, requiring INR monitoring.
Antidiabetic agents
May increase blood glucose levels, requiring dose adjustment of antidiabetic drugs.
Diuretics (e.g., Furosemide)
May enhance potassium depletion, increasing risk of hypokalemia.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare. Management involves symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Daprosis is excreted in breast milk; caution advised during lactation.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to Daprosis or any component of the formulation
- Live or live-attenuated vaccines during immunosuppressive doses
Drug Interactions
NSAIDs
Increased risk of gastrointestinal ulceration and bleeding.
Warfarin
May enhance or diminish anticoagulant effects, requiring INR monitoring.
Antidiabetic agents
May increase blood glucose levels, requiring dose adjustment of antidiabetic drugs.
Diuretics (e.g., Furosemide)
May enhance potassium depletion, increasing risk of hypokalemia.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare. Management involves symptomatic and supportive treatment. No specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Daprosis is excreted in breast milk; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by DGDA
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Daprosis has been extensively studied in clinical trials for its efficacy and safety in various inflammatory and autoimmune conditions.
Lab Monitoring
- Blood glucose levels (especially in diabetic patients)
- Electrolyte levels (potassium, sodium)
- Blood pressure monitoring
- Bone density (with long-term use)
Doctor Notes
- Consider the lowest effective dose for the shortest possible duration.
- Taper the dose gradually when discontinuing treatment to prevent adrenal insufficiency.
- Monitor patients for signs of infection and metabolic disturbances.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not stop taking Daprosis abruptly without medical advice.
- Report any unusual or severe side effects to your doctor immediately.
- Carry a steroid card if you are on long-term therapy.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Daprosis may cause dizziness or blurred vision in some patients, so caution is advised when driving or operating heavy machinery.
Lifestyle Advice
- Maintain a healthy and balanced diet.
- Engage in regular, moderate exercise to support bone health.
- Avoid smoking and excessive alcohol consumption.
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