Delfex
Generic Name
Fexofenadine Hydrochloride 120 mg Tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| delfex 120 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Delfex 120 mg Tablet is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, and hives. It works by blocking a natural substance (histamine) that your body makes during an allergic reaction.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis and chronic idiopathic urticaria: 120 mg or 180 mg once daily.
Elderly
No dose adjustment generally required, but caution with renal impairment.
Renal_impairment
For patients with impaired renal function (creatinine clearance < 80 mL/min), a starting dose of 60 mg once daily is recommended.
How to Take
Take the tablet orally with water, with or without food. Do not take with fruit juice as it may reduce absorption.
Mechanism of Action
Fexofenadine is a selective peripheral H1-blocker. It inhibits histamine release from mast cells and reduces the effects of histamine on H1-receptors, thereby alleviating allergic symptoms without causing significant sedation.
Pharmacokinetics
Onset
Approximately 1 hour for significant symptom relief.
Excretion
Primarily excreted in feces (approximately 80%) and urine (approximately 11%) as unchanged drug.
Half life
11-15 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached in 1-3 hours.
Metabolism
Approximately 5% of the dose is metabolized, primarily by the hepatic route.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any components of the tablet
- Children under 6 years of age for 120 mg or 180 mg strength
Drug Interactions
Erythromycin or Ketoconazole
May increase plasma levels of fexofenadine.
Antacids containing Aluminum or Magnesium
May decrease fexofenadine absorption if taken simultaneously. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive; no specific antidote. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks. Excreted in breast milk, caution advised. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any components of the tablet
- Children under 6 years of age for 120 mg or 180 mg strength
Drug Interactions
Erythromycin or Ketoconazole
May increase plasma levels of fexofenadine.
Antacids containing Aluminum or Magnesium
May decrease fexofenadine absorption if taken simultaneously. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive; no specific antidote. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks. Excreted in breast milk, caution advised. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Available in pharmacies, hospitals, and clinics
Approval Status
Approved by FDA (USA), DGDA (Bangladesh)
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of fexofenadine for seasonal allergic rhinitis and chronic idiopathic urticaria.
Lab Monitoring
- No routine lab monitoring is generally required. Patients with renal impairment might need monitoring of renal function if other co-morbidities exist.
Doctor Notes
- Counsel patients to avoid fruit juices within 2 hours of dose.
- Advise patients about potential for mild drowsiness, although it is generally non-sedating.
- Important to distinguish between acute and chronic urticaria for appropriate management.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Avoid alcohol while taking this medicine.
- Do not take with fruit juice.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause drowsiness in some individuals. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Identify and avoid known allergens.
- Keep windows closed during high pollen seasons.
- Use air purifiers at home.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Delfex Brand
Other medicines available under the same brand name
