Demacro
Generic Name
Dequalinium Chloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| demacro 500 mg tablet | ৳ 30.00 | N/A |
| demacro 200 mg suspension | ৳ 85.00 | N/A |
Description
Overview of the medicine
Demacro is a lozenge containing Dequalinium Chloride, used for local treatment of oral and pharyngeal infections such as sore throat, stomatitis, and gingivitis.
Uses & Indications
Dosage
Adults
1 lozenge slowly dissolved in the mouth every 2-3 hours, up to a maximum of 8-10 lozenges per day.
Elderly
Same as adult dosage.
Renal_impairment
No specific dose adjustment needed due to minimal systemic absorption.
How to Take
Allow the lozenge to dissolve slowly in the mouth. Do not chew or swallow whole. Avoid eating or drinking immediately after administration to allow the active ingredient to work.
Mechanism of Action
Dequalinium chloride is a quaternary ammonium compound with broad-spectrum bactericidal and fungicidal activity. It acts by disrupting bacterial cell membranes and inhibiting enzyme activity.
Pharmacokinetics
Onset
Rapid local action, within minutes of dissolving.
Excretion
Primarily excreted locally or via saliva; minimal systemic excretion.
Half life
Not relevant for local action/minimal systemic absorption.
Absorption
Minimal systemic absorption from oral cavity.
Metabolism
Negligible systemic metabolism due to minimal absorption.
Side Effects
Contraindications
- •Hypersensitivity to Dequalinium Chloride or any component of the formulation.
Drug Interactions
Antiseptics
Concomitant use with other local antiseptics is generally not recommended as it may reduce efficacy or cause irritation.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture.
Overdose
Overdose is unlikely with lozenges due to local action and minimal absorption. Ingestion of a very large number of lozenges may lead to gastrointestinal upset. Symptomatic treatment is recommended.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation due to minimal systemic absorption, but consult a doctor if necessary.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
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Global Brand Names
International brand names for this medicine
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