Dexamin
Generic Name
Dexamethasone 5 mg Injection
Manufacturer
Example Pharmaceutical Co. Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dexamin 5 mg injection | ৳ 18.05 | N/A |
Description
Overview of the medicine
Dexamethasone is a potent synthetic corticosteroid used for various inflammatory and autoimmune conditions. It has potent anti-inflammatory and immunosuppressant properties.
Uses & Indications
Dosage
Adults
Varies widely based on condition and severity, typically 0.5 mg to 9 mg daily, given IM or IV. For COVID-19, 6 mg once daily for up to 10 days.
Elderly
Lower doses may be required, careful monitoring due to potential for increased side effects.
Renal_impairment
No specific dose adjustment typically needed, but caution with fluid retention.
How to Take
Administered by a healthcare professional directly into a vein or muscle. Doses should be slowly injected.
Mechanism of Action
Binds to glucocorticoid receptors, modulating gene expression to produce anti-inflammatory and immunosuppressive effects. It inhibits the release of inflammatory mediators.
Pharmacokinetics
Onset
Rapid (minutes for IV)
Excretion
Excreted mainly in the urine, primarily as inactive metabolites.
Half life
Biological half-life is 36-54 hours. Plasma half-life is 2.2-3.8 hours.
Absorption
Rapidly absorbed after intramuscular or intravenous administration. Peak plasma concentration achieved within minutes (IV) to hours (IM).
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to dexamethasone or any component
- Live virus vaccines during corticosteroid therapy
Drug Interactions
NSAIDs
Increased risk of gastrointestinal ulceration.
Diuretics
Increased potassium loss.
Anticoagulants
May alter anticoagulant effects.
Insulin/Oral Hypoglycemics
May increase blood glucose, requiring dosage adjustment.
Phenytoin, Phenobarbital, Rifampicin
May decrease dexamethasone levels.
Storage
Store at room temperature (15-30°C), protected from light. Do not freeze.
Overdose
Symptoms include fluid retention, hypertension, hyperglycemia, electrolyte imbalance. Management is symptomatic and supportive.
Pregnancy & Lactation
Use with caution, only if potential benefits outweigh risks. Can cross the placenta and be excreted in breast milk. Consult a doctor.
Side Effects
Contraindications
- Systemic fungal infections
- Hypersensitivity to dexamethasone or any component
- Live virus vaccines during corticosteroid therapy
Drug Interactions
NSAIDs
Increased risk of gastrointestinal ulceration.
Diuretics
Increased potassium loss.
Anticoagulants
May alter anticoagulant effects.
Insulin/Oral Hypoglycemics
May increase blood glucose, requiring dosage adjustment.
Phenytoin, Phenobarbital, Rifampicin
May decrease dexamethasone levels.
Storage
Store at room temperature (15-30°C), protected from light. Do not freeze.
Overdose
Symptoms include fluid retention, hypertension, hyperglycemia, electrolyte imbalance. Management is symptomatic and supportive.
Pregnancy & Lactation
Use with caution, only if potential benefits outweigh risks. Can cross the placenta and be excreted in breast milk. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years, check specific product packaging.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Widely studied. Recent trials confirmed its benefit in severe COVID-19.
Lab Monitoring
- Blood glucose levels
- Electrolyte levels (especially potassium)
- Blood pressure
- Bone density (for long-term use)
- Adrenal function tests
Doctor Notes
- Taper dose slowly if discontinuing after prolonged use.
- Monitor for signs of infection, especially in immunocompromised patients.
- Caution in patients with diabetes, hypertension, or a history of peptic ulcer.
Patient Guidelines
- Do not stop this medicine abruptly without consulting your doctor.
- Report any signs of infection immediately.
- Monitor blood sugar if you are diabetic.
- Follow a low-sodium, high-potassium diet if advised.
Missed Dose Advice
Contact your doctor or nurse for advice. Do not double the dose.
Driving Precautions
May cause dizziness or vision changes in some individuals. Exercise caution when driving or operating machinery until you know how it affects you.
Lifestyle Advice
- Maintain good hygiene to prevent infections.
- Engage in weight-bearing exercises (if appropriate) to support bone health.
- Avoid exposure to people with contagious diseases.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Dexamin Brand
Other medicines available under the same brand name
