For rectal use only. Remove the suppository from its wrapper. Lie on your side and insert the suppository, pointed end first, into the rectum. Remain lying down for a few minutes to allow it to dissolve. Wash hands before and after use.

Painorelaxone acts on the central nervous system, specifically in the brain stem and spinal cord, to produce its muscle relaxant effects. It may enhance GABAergic activity or inhibit polysynaptic reflexes, leading to decreased muscle tone and spasm.

• •Hypersensitivity to Painorelaxone or any components
• •Severe hepatic or renal impairment
• •Acute narrow-angle glaucoma
• •Myasthenia gravis

Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms may include severe drowsiness, confusion, dizziness, blurred vision, hypotension, and respiratory depression. Management involves supportive care, maintaining airway, and monitoring vital signs. Gastric lavage is not applicable for suppositories.

Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks. Excreted in breast milk; avoid during lactation or use with caution and monitor infant for adverse effects.