Take orally once daily, with or without food. Swallow the tablet whole with a glass of water. It is advisable to take the medicine at the same time each day.

Amlodipine inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. It produces vasodilation by acting directly on vascular smooth muscle, leading to a reduction in peripheral vascular resistance and blood pressure.

• •Hypersensitivity to Amlodipine or other dihydropyridine derivatives
• •Severe hypotension
• •Cardiogenic shock
• •Obstructive outflow tract disease (e.g., severe aortic stenosis)
• •Hemodynamically unstable heart failure after acute myocardial infarction

Store in a cool and dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose include excessive peripheral vasodilation with marked hypotension and possibly reflex tachycardia. Management involves active cardiac and respiratory monitoring, frequent blood pressure measurements, and supportive measures such as elevation of limbs, judicious administration of fluids, and vasopressors if necessary.

Pregnancy: Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation: Amlodipine is excreted in human milk. Consult doctor before use during lactation.