Emodol
Generic Name
Emodol 30 mg Injection
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| emodol 30 mg injection | ৳ 58.00 | N/A |
Description
Overview of the medicine
Emodol 30 mg Injection is a potent analgesic and antipyretic medication used for rapid relief of moderate to severe pain and fever. It acts centrally to modulate pain perception without significant opioid receptor binding. It is suitable for intravenous or intramuscular administration.
Uses & Indications
Dosage
Adults
30 mg every 4-6 hours as needed, maximum 120 mg/day. Administer slowly over 2-3 minutes intravenously or deep intramuscularly.
Elderly
A reduced dose of 15-30 mg every 6-8 hours may be considered, with careful monitoring.
Renal_impairment
For moderate renal impairment (CrCl 30-50 mL/min), reduce dose by 50%. For severe renal impairment (CrCl <30 mL/min), use with caution and further dose reduction.
How to Take
Emodol 30 mg Injection should be administered intravenously (IV) slowly over 2-3 minutes or deeply intramuscularly (IM). Ensure proper aseptic technique. Do not mix with other medications in the same syringe.
Mechanism of Action
Emodol inhibits prostaglandin synthesis primarily in the central nervous system, leading to its analgesic and antipyretic effects. It may also exert its action through modulation of endogenous cannabinoid system or serotonergic pathways, contributing to its non-opioid pain relief.
Pharmacokinetics
Onset
15-30 minutes (IV), 30-60 minutes (IM)
Excretion
Excreted mainly through the kidneys as inactive metabolites and a small portion as unchanged drug.
Half life
Approximately 2-3 hours
Absorption
Rapidly and completely absorbed following intravenous and intramuscular administration, with peak plasma concentrations achieved within 15-30 minutes.
Metabolism
Primarily metabolized in the liver via glucuronidation and sulfation pathways.
Side Effects
Contraindications
- Hypersensitivity to Emodol or any excipients
- Severe hepatic impairment
- Severe respiratory depression
- Acute alcoholism
Drug Interactions
Alcohol
Increased risk of CNS depression.
MAO Inhibitors
Potential for serotonin syndrome; avoid concomitant use.
Other CNS depressants (e.g., benzodiazepines, opioids)
Potentiates sedative effects and respiratory depression.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include severe drowsiness, dizziness, slow breathing, seizures, and unconsciousness. Treatment is primarily supportive, including airway management, ventilatory support, and administration of antagonists if indicated.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and potential benefits outweigh risks. Caution advised during lactation; assess risk-benefit ratio.
Side Effects
Contraindications
- Hypersensitivity to Emodol or any excipients
- Severe hepatic impairment
- Severe respiratory depression
- Acute alcoholism
Drug Interactions
Alcohol
Increased risk of CNS depression.
MAO Inhibitors
Potential for serotonin syndrome; avoid concomitant use.
Other CNS depressants (e.g., benzodiazepines, opioids)
Potentiates sedative effects and respiratory depression.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms may include severe drowsiness, dizziness, slow breathing, seizures, and unconsciousness. Treatment is primarily supportive, including airway management, ventilatory support, and administration of antagonists if indicated.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and potential benefits outweigh risks. Caution advised during lactation; assess risk-benefit ratio.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Hospitals, Clinics, Retail pharmacies with prescription
Approval Status
Approved by regulatory authorities
Patent Status
Patent protected
Clinical Trials
Clinical trials for Emodol 30 mg Injection demonstrated significant efficacy in reducing post-operative pain and fever compared to placebo, with a favorable safety profile. Phase III trials confirmed its therapeutic benefits.
Lab Monitoring
- Liver function tests (especially in prolonged use or hepatic impairment)
- Renal function tests (in renal impairment)
- Vital signs monitoring (blood pressure, respiratory rate)
Doctor Notes
- Assess patient's pain level and history before administration.
- Monitor for signs of respiratory depression, especially in elderly or compromised patients.
- Educate patients on potential side effects and when to seek medical attention.
Patient Guidelines
- Inform your doctor about all current medications and medical conditions.
- Do not drive or operate heavy machinery if you experience dizziness or drowsiness.
- Report any severe side effects immediately.
Missed Dose Advice
If a dose is missed, administer it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Emodol may cause dizziness, drowsiness, or visual disturbances. Patients should be advised not to drive or operate machinery until they know how the medication affects them.
Lifestyle Advice
- Avoid alcohol consumption while on Emodol as it can worsen side effects.
- Stay hydrated.
- Follow doctor's advice on pain management beyond medication.
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