Oral administration. Shake the suspension well before each use. Can be taken with or without food, but taking it with food may reduce gastrointestinal upset. Complete the full course of treatment as prescribed, even if symptoms improve.

Erythromycin binds to the 50S ribosomal subunit of susceptible microorganisms, thereby inhibiting protein synthesis without affecting nucleic acid synthesis. This leads to a bacteriostatic effect, though it can be bactericidal at high concentrations or against highly susceptible organisms.

• •Hypersensitivity to erythromycin or any macrolide antibiotic
• •Co-administration with terfenadine, astemizole, cisapride, pimozide, or colchicine (due to risk of cardiac arrhythmias or severe toxicity)
• •Pre-existing hepatic disease

Store dry powder below 30°C, protected from light and moisture. After reconstitution, store in a refrigerator (2-8°C) and discard unused portion after the specified period (e.g., 7 or 14 days).

Symptoms of overdose include severe nausea, vomiting, diarrhea, and abdominal discomfort. Acute pancreatitis and reversible hearing loss may also occur. Treatment is supportive, focusing on gastric lavage and symptomatic management. Hemodialysis is not effective.

Pregnancy Category B. Generally considered safe, but use only if clearly needed. Erythromycin is excreted in breast milk; caution is advised, but usually compatible with breastfeeding with monitoring for infant side effects.