Eryzen
Generic Name
Erythromycin 250 mg tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| eryzen 250 mg tablet | ৳ 4.38 | ৳ 26.28 |
Description
Overview of the medicine
Erythromycin is a macrolide antibiotic used to treat a wide range of bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted diseases.
Uses & Indications
Dosage
Adults
250-500 mg every 6-12 hours, depending on the severity of the infection and specific indication. Usually 250 mg four times daily or 500 mg twice daily.
Elderly
No specific dose adjustment based on age alone, but caution with renal or hepatic impairment.
Renal_impairment
No dosage adjustment necessary for mild to moderate renal impairment. For severe impairment (CrCl <10 mL/min), dosage reduction may be considered.
How to Take
Orally, with a full glass of water. Can be taken with or without food, but some forms are better absorbed on an empty stomach.
Mechanism of Action
Binds to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis.
Pharmacokinetics
Onset
Within 1-2 hours for antibacterial action.
Excretion
Mainly excreted in bile and feces; a small portion is excreted in urine.
Half life
Approximately 1.5-2 hours.
Absorption
Well absorbed orally, but absorption varies. Food can impact absorption for some formulations.
Metabolism
Extensively metabolized in the liver, primarily by the cytochrome P450 3A4 (CYP3A4) enzyme system.
Side Effects
Contraindications
- •Hypersensitivity to erythromycin or any macrolide antibiotic
- •Co-administration with cisapride, pimozide, or ergot alkaloids due to risk of serious arrhythmias
- •History of cholestatic jaundice/hepatic dysfunction associated with prior erythromycin use
Drug Interactions
Digoxin
Increased digoxin levels.
Warfarin
Increased anticoagulant effect, leading to bleeding risk.
Carbamazepine
Increased carbamazepine levels, leading to toxicity.
Cisapride, Pimozide, Ergot alkaloids
Significant risk of QT prolongation and serious arrhythmias. Contraindicated.
Statins (e.g., simvastatin, lovastatin)
Increased risk of myopathy/rhabdomyolysis.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include severe nausea, vomiting, abdominal pain, diarrhea, and reversible hearing loss. Treatment is symptomatic and supportive; gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category B. Generally considered safe during pregnancy, but use only if clearly needed. Excreted in breast milk; caution advised, observe infant for GI disturbances.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
