Eryzen 500 mg Tablet should be taken orally, preferably on an empty stomach (1 hour before or 2 hours after meals) with a glass of water for optimal absorption. If stomach upset occurs, it may be taken with food.

Erythromycin binds to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This action is primarily bacteriostatic, but can be bactericidal at higher concentrations.

• •Known hypersensitivity to erythromycin or any other macrolide antibiotics.
• •Co-administration with terfenadine, astemizole, cisapride, pimozide, or colchicine due to risk of serious and/or life-threatening cardiac arrhythmias (QT prolongation).
• •Patients with pre-existing liver disease or cholestatic jaundice.

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Symptoms of overdose include severe nausea, vomiting, abdominal pain, and diarrhea. Hepatic dysfunction and reversible hearing loss may also occur. Management involves gastric lavage, supportive care, and monitoring of vital signs and cardiac function. Erythromycin is not removed by peritoneal dialysis or hemodialysis.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. Limited data in pregnant women suggest no increased risk of major congenital anomalies. Use during pregnancy only if clearly needed. Erythromycin is excreted in breast milk; use with caution in nursing mothers.