Reconstitute the dry powder with boiled and cooled water as directed on the label. Shake the bottle well before each use. Take the medicine orally, with or without food. Taking it with food may help reduce potential gastrointestinal upset. Use the provided measuring spoon or cup for accurate dosing.

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bacterial cell lysis. Clavulanic acid is a beta-lactamase inhibitor that irreversibly binds to and inactivates beta-lactamase enzymes produced by resistant bacteria, thereby extending the antibacterial spectrum of amoxicillin.

• •History of hypersensitivity to penicillin or other beta-lactam antibiotics (e.g., cephalosporins)
• •Previous history of amoxicillin-clavulanate associated jaundice or hepatic dysfunction

Store the dry powder below 30°C in a dry place, away from direct sunlight. Once reconstituted, store the suspension in a refrigerator (2-8°C) and do not freeze.

Symptoms of overdose may include gastrointestinal symptoms (nausea, vomiting, diarrhea), fluid and electrolyte imbalance, and crystalluria (renal failure in severe cases). Management is symptomatic and supportive, with attention to fluid and electrolyte balance. Amoxicillin/clavulanate can be removed from circulation by hemodialysis.

Pregnancy Category B. Studies in animals have not shown a risk, but there are no adequate and well-controlled studies in pregnant women. Use only if clearly needed. Both amoxicillin and clavulanic acid are excreted into human milk in small amounts; use with caution during breastfeeding.