Fenat
Generic Name
Finasteride
Manufacturer
Medipharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fenat 1 mg tablet | ৳ 3.00 | ৳ 30.00 |
Description
Overview of the medicine
Finasteride 1 mg is used for the treatment of male pattern hair loss (androgenetic alopecia) in men.
Uses & Indications
Dosage
Adults
1 mg orally once daily. May be taken with or without food.
Elderly
No dosage adjustment is generally required for elderly patients.
Renal_impairment
No dosage adjustment is necessary in patients with renal impairment.
How to Take
Take the tablet orally once daily, with or without food. Do not crush or break the tablet.
Mechanism of Action
Finasteride selectively inhibits the enzyme 5-alpha reductase type 2, which is responsible for converting testosterone to dihydrotestosterone (DHT). By reducing DHT levels in the scalp, it helps to slow hair loss and promote new hair growth.
Pharmacokinetics
Onset
Clinical effects typically begin to be noticeable after 3-6 months of consistent use.
Excretion
Excreted as metabolites primarily through feces (57%) and urine (39%).
Half life
Approximately 5-6 hours in healthy young men. In men over 70 years, the half-life is approximately 8 hours.
Absorption
Well absorbed after oral administration, bioavailability is approximately 65%. Peak plasma concentrations are reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily via the CYP450 3A4 enzyme, into two active metabolites.
Side Effects
Contraindications
- Hypersensitivity to finasteride or any component of the tablet.
- Pregnancy and women of childbearing potential.
- Children.
Drug Interactions
No significant interactions
Finasteride does not appear to interact significantly with other commonly used medications.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Management should be symptomatic and supportive.
Pregnancy & Lactation
Finasteride is contraindicated in women, especially pregnant women or women of childbearing potential, due to the risk of causing abnormalities of the external genitalia of a male fetus. It is not indicated for use in women and it is unknown if finasteride is excreted in human milk.
Side Effects
Contraindications
- Hypersensitivity to finasteride or any component of the tablet.
- Pregnancy and women of childbearing potential.
- Children.
Drug Interactions
No significant interactions
Finasteride does not appear to interact significantly with other commonly used medications.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Management should be symptomatic and supportive.
Pregnancy & Lactation
Finasteride is contraindicated in women, especially pregnant women or women of childbearing potential, due to the risk of causing abnormalities of the external genitalia of a male fetus. It is not indicated for use in women and it is unknown if finasteride is excreted in human milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture.
Availability
Pharmacies, hospitals
Approval Status
Approved (e.g., FDA, DGDA)
Patent Status
Off-patent (generics available)
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of finasteride 1 mg for the treatment of male pattern hair loss.
Lab Monitoring
- Prostate-Specific Antigen (PSA) levels: Finasteride can decrease PSA levels. Physicians should adjust PSA values when interpreting results from treated men.
Doctor Notes
- Counsel male patients on potential sexual side effects and the importance of long-term adherence for efficacy.
- Advise patients not to donate blood while on finasteride and for at least one month after stopping due to potential risk to pregnant transfusions.
- Monitor PSA levels and adjust interpretation based on finasteride use.
Patient Guidelines
- Take this medicine regularly as prescribed by your doctor.
- Do not allow women, especially pregnant women, to handle crushed or broken tablets due to potential risk to a male fetus.
- Be aware that it may take 3 to 6 months to see the full benefits of treatment.
- Report any changes in breast tissue (e.g., lumps, pain, nipple discharge) to your doctor immediately.
Missed Dose Advice
If you miss a dose, take the next dose as scheduled. Do not take a double dose to make up for a missed one.
Driving Precautions
Finasteride is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintaining a healthy lifestyle, including a balanced diet and managing stress, can support overall hair health.
- Consult with a dermatologist or healthcare provider for comprehensive hair loss management strategies.
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Global Brand Names
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