Fenobac
Generic Name
Hypothetical Fenobac Compound
Manufacturer
Global Pharma Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fenobac 5 mg oral solution | ৳ 100.00 | N/A |
Description
Overview of the medicine
Fenobac 5 mg Oral Solution is a non-steroidal anti-inflammatory drug (NSAID)-like agent used for the symptomatic relief of mild to moderate pain and inflammation. It is formulated as an oral solution for easy administration, especially in pediatric and geriatric patients.
Uses & Indications
Dosage
Adults
5 mg (1 teaspoon) orally every 6-8 hours as needed, not exceeding 20 mg in 24 hours.
Elderly
Initiate with a lower dose (e.g., 2.5 mg) and adjust based on response and tolerability, due to potential reduced renal function.
Renal_impairment
Use with caution. Dosage reduction may be necessary in severe impairment. Not recommended for eGFR < 30 mL/min.
How to Take
Take orally with or without food. Measure the dose accurately using the provided measuring spoon or cup. Shake the bottle well before use.
Mechanism of Action
Fenobac is thought to exert its therapeutic effects by inhibiting cyclooxygenase (COX) enzymes, leading to reduced prostaglandin synthesis. This action helps to mitigate pain, fever, and inflammation. Its exact COX selectivity may vary.
Pharmacokinetics
Onset
Pain relief typically begins within 30 minutes, with maximum effect in 1-2 hours.
Excretion
Excreted predominantly in the urine (60-70%) as metabolites, with some fecal excretion (20-30%).
Half life
Approximately 2-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 30-60 minutes.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes (e.g., CYP2C9 and CYP2C19), forming inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to Fenobac or other NSAIDs
- •Active gastrointestinal bleeding or peptic ulcer
- •Severe renal or hepatic impairment
- •Third trimester of pregnancy
- •Severe uncontrolled heart failure
Drug Interactions
Lithium
Increased plasma lithium levels, leading to toxicity.
Warfarin
Increased risk of bleeding due to enhanced anticoagulant effect.
Diuretics
Reduced diuretic and antihypertensive effects; increased risk of nephrotoxicity.
Methotrexate
Increased methotrexate toxicity.
ACE Inhibitors/ARBs
Reduced antihypertensive effect; increased risk of renal impairment.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, epigastric pain, lethargy, drowsiness, and rarely, gastrointestinal bleeding, acute renal failure, and respiratory depression. Management includes supportive and symptomatic treatment, gastric lavage, and activated charcoal.
Pregnancy & Lactation
Not recommended during the third trimester of pregnancy due to potential fetal harm and complications during delivery. Use with caution during the first and second trimesters only if clearly needed. Excreted in breast milk, caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by Regulatory Authority
Patent Status
Patent Pending
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Global Brand Names
International brand names for this medicine
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