Fenobac
Generic Name
Fenobac
Manufacturer
Meditopix Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fenobac 5 mg tablet | ৳ 5.50 | ৳ 55.00 |
Description
Overview of the medicine
Fenobac 5 mg Tablet is an anti-inflammatory drug used to relieve pain, swelling, and inflammation associated with various conditions.
Uses & Indications
Dosage
Adults
The usual adult dose is 5 mg once or twice daily, or as prescribed by a physician. Doses should be taken preferably with food.
Elderly
Elderly patients may require a lower starting dose due to increased risk of adverse effects. Close monitoring of renal function is recommended.
Renal_impairment
Dose adjustment is necessary in patients with moderate to severe renal impairment. Consult physician for specific dosage guidance or consider alternative treatments.
How to Take
Fenobac 5 mg Tablet should be taken orally, preferably with food or milk to minimize gastrointestinal upset. Swallow the tablet whole with a glass of water.
Mechanism of Action
Fenobac inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the synthesis of prostaglandins. By reducing prostaglandin production, it diminishes inflammation, pain, and fever.
Pharmacokinetics
Onset
The analgesic and anti-inflammatory effects typically begin within 30 to 60 minutes after administration.
Excretion
The drug and its metabolites are predominantly excreted via the kidneys (urine), with a minor portion excreted through bile.
Half life
The elimination half-life of Fenobac ranges from 6 to 8 hours.
Absorption
Fenobac is rapidly absorbed from the gastrointestinal tract following oral administration. Peak plasma concentrations are usually achieved within 1 to 2 hours.
Metabolism
Fenobac is primarily metabolized in the liver, mainly by cytochrome P450 (CYP) enzymes, into inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to Fenobac or any other NSAIDs (e.g., aspirin, ibuprofen)
- •History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- •Active gastrointestinal bleeding or peptic ulcer disease
- •Severe renal or hepatic impairment
- •Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels, leading to potential toxicity.
Methotrexate
Increased plasma methotrexate levels, potentially enhancing its toxicity.
ACE Inhibitors/ARBs
Reduced antihypertensive effect and increased risk of renal dysfunction, especially in elderly or dehydrated patients.
Diuretics (e.g., Furosemide)
Reduced diuretic and antihypertensive effects, increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding. Close monitoring of INR is required.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, epigastric pain, lethargy, and drowsiness. Rare symptoms include gastrointestinal bleeding, acute renal failure, and respiratory depression. Management includes gastric lavage, activated charcoal, and symptomatic and supportive treatment. There is no specific antidote.
Pregnancy & Lactation
Pregnancy: Use of NSAIDs, including Fenobac, during the third trimester of pregnancy is contraindicated due to the risk of premature closure of the fetal ductus arteriosus. Use during early pregnancy should only be if the potential benefit outweighs the risk. Lactation: Fenobac is excreted in breast milk in small amounts. Use with caution during lactation; consult a healthcare professional.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the date of manufacture when stored under recommended conditions.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Patented
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Global Brand Names
International brand names for this medicine
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