Fexocon
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Beximco Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fexocon 120 mg tablet | ৳ 7.50 | ৳ 75.00 |
Description
Overview of the medicine
Fexofenadine is a second-generation antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives. It works by blocking histamine, a natural substance that the body produces during an allergic reaction.
Uses & Indications
Dosage
Adults
120 mg once daily or 60 mg twice daily
Elderly
No specific dose adjustment is generally required, but caution is advised in patients with impaired renal function.
Renal_impairment
Initial dose of 60 mg once daily is recommended for patients with impaired renal function.
How to Take
Oral. Should be taken with water, preferably before a meal. Do not take with fruit juice.
Mechanism of Action
Fexofenadine is a selective peripheral H1-blocker. It inhibits histamine release from mast cells and reduces the effects of histamine on H1 receptors, thereby alleviating allergic symptoms.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily excreted unchanged in feces (approximately 80%) and urine (approximately 10%).
Half life
11-15 hours
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in 1-3 hours.
Metabolism
Minimally metabolized (approximately 5% of total dose) in the liver via cytochrome P450 enzymes. Primarily, it undergoes minimal biotransformation.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients
- Children under 6 years of age
Drug Interactions
Erythromycin
Increased fexofenadine plasma levels
Ketoconazole
Increased fexofenadine plasma levels
Antacids containing aluminum or magnesium
Decreased fexofenadine absorption
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive, including gastric lavage and activated charcoal if appropriate.
Pregnancy & Lactation
Use in pregnancy only if clearly needed after careful risk-benefit assessment. Fexofenadine is excreted into breast milk; caution is advised in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients
- Children under 6 years of age
Drug Interactions
Erythromycin
Increased fexofenadine plasma levels
Ketoconazole
Increased fexofenadine plasma levels
Antacids containing aluminum or magnesium
Decreased fexofenadine absorption
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive, including gastric lavage and activated charcoal if appropriate.
Pregnancy & Lactation
Use in pregnancy only if clearly needed after careful risk-benefit assessment. Fexofenadine is excreted into breast milk; caution is advised in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies
Approval Status
Approved
Patent Status
Expired
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of fexofenadine for allergic rhinitis and chronic urticaria.
Lab Monitoring
- No specific routine lab monitoring required.
Doctor Notes
- Advise patients to avoid taking with fruit juices due to reduced absorption.
- Consider dose adjustment in patients with renal impairment.
- Fexofenadine is a good choice for patients requiring a non-sedating antihistamine.
Patient Guidelines
- Do not exceed the recommended dose.
- Avoid taking with fruit juices.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose.
Driving Precautions
Fexofenadine is generally non-drowsy, but individual responses vary. Patients should assess their response before driving or operating machinery.
Lifestyle Advice
- Identify and avoid allergy triggers.
- Maintain good hygiene to reduce allergen exposure.
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Global Brand Names
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