Take orally with water, preferably before a meal. Do not take with fruit juice (e.g., grapefruit, orange, apple) as these can significantly reduce absorption. Avoid taking antacids containing aluminum or magnesium within 2 hours of this medicine.

Fexofenadine selectively blocks peripheral H1 histamine receptors, thereby preventing the binding of histamine and inhibiting the subsequent allergic reactions such as vasodilation, increased capillary permeability, and smooth muscle contraction. Unlike first-generation antihistamines, it has minimal penetration of the blood-brain barrier, resulting in low sedative effects.

• •Known hypersensitivity to fexofenadine or any excipients present in the tablet formulation.

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children. Do not freeze.

Limited information is available on fexofenadine overdose. Symptoms reported include dizziness, drowsiness, and dry mouth. Management should be symptomatic and supportive. Hemodialysis does not effectively remove fexofenadine from the blood.

Pregnancy Category C. Studies in animals have shown adverse effects on the fetus, but there are no adequate and well-controlled studies in pregnant women. Use only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; therefore, caution should be exercised when administered to a nursing woman. Consult a doctor before use during pregnancy or lactation.