Fexona
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fexona 120 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Fexona 120 mg Tablet contains Fexofenadine Hydrochloride, a non-sedating antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). It helps reduce sneezing, runny nose, itchy watery eyes, and skin itching or rashes.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 120 mg once daily. For chronic idiopathic urticaria: 180 mg once daily (use Fexofenadine 180 mg tablet if available).
Elderly
No dosage adjustment is generally required in elderly patients, unless renal impairment is present.
Renal_impairment
In patients with impaired renal function, a starting dose of 60 mg once daily is recommended for seasonal allergic rhinitis and chronic idiopathic urticaria.
How to Take
Take the tablet orally with water, preferably before a meal. Do not take with fruit juices (grapefruit, orange, apple) as they may reduce absorption.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It blocks histamine, a natural substance produced by the body during an allergic reaction, thereby preventing and relieving allergy symptoms without significantly crossing the blood-brain barrier, which minimizes sedation.
Pharmacokinetics
Onset
Within 1 hour.
Excretion
Primarily excreted unchanged in feces (approximately 80%) and urine (approximately 10%).
Half life
Approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached in 1-3 hours.
Metabolism
Minimally metabolized (approximately 5% hepatic metabolism).
Side Effects
Contraindications
- Known hypersensitivity to Fexofenadine or any components of the tablet.
Drug Interactions
Erythromycin and Ketoconazole
May increase Fexofenadine plasma levels, but no clinically significant increase in adverse effects has been reported.
Aluminum- or Magnesium-containing Antacids
May decrease Fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment is recommended. Hemodialysis does not effectively remove Fexofenadine from blood.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; therefore, caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Known hypersensitivity to Fexofenadine or any components of the tablet.
Drug Interactions
Erythromycin and Ketoconazole
May increase Fexofenadine plasma levels, but no clinically significant increase in adverse effects has been reported.
Aluminum- or Magnesium-containing Antacids
May decrease Fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment is recommended. Hemodialysis does not effectively remove Fexofenadine from blood.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; therefore, caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date
Availability
Available in pharmacies nationwide
Approval Status
Approved (in Bangladesh and globally)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Fexofenadine has undergone extensive clinical trials demonstrating its efficacy and safety for allergic rhinitis and chronic urticaria. Ongoing post-marketing surveillance continues to monitor its use.
Lab Monitoring
- Routine laboratory monitoring is generally not required.
Doctor Notes
- Advise patients about the non-sedating nature, but counsel on potential for individual variations.
- Emphasize the importance of avoiding fruit juices due to significant reduction in bioavailability.
- Consider renal dose adjustment in patients with kidney impairment.
Patient Guidelines
- Do not exceed the recommended dose.
- Avoid consuming fruit juices within 2 hours of taking this medicine.
- Consult your doctor or pharmacist if symptoms do not improve within a few days or worsen.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Fexona is a non-sedating antihistamine, but some individuals may experience drowsiness or dizziness. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Identify and avoid known allergens that trigger your symptoms.
- Maintain good hygiene and a clean living environment.
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Global Brand Names
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