Fexoral
Generic Name
fexoral-120-mg-tablet
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fexoral 120 mg tablet | ৳ 9.00 | ৳ 90.00 |
Description
Overview of the medicine
Fexofenadine is a non-sedating antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives.
Uses & Indications
Dosage
Adults
120 mg once daily, or 60 mg twice daily if preferred for some conditions.
Elderly
No specific dose adjustment is usually required, but caution is advised in elderly patients with impaired renal function.
Renal_impairment
Initial dose of 60 mg once daily is recommended for patients with impaired renal function.
How to Take
Take orally with water, with or without food. Do not take with fruit juice.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It blocks the action of histamine, a natural substance in the body that causes allergic symptoms.
Pharmacokinetics
Onset
Approximately 1 hour
Excretion
Primarily excreted unchanged in feces (approx. 80%) and urine (approx. 10%).
Half life
Approximately 14-16 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, reaching peak plasma concentrations in 1-3 hours.
Metabolism
Minimally metabolized in the liver; approximately 5% undergoes hepatic metabolism.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients.
- Children under 6 years for 120mg/180mg tablets.
Drug Interactions
Erythromycin/Ketoconazole
Can increase plasma levels of fexofenadine, but generally without increased adverse effects.
Antacids (containing aluminum and magnesium)
May reduce the absorption of fexofenadine. Take antacids at least 2 hours apart from fexofenadine.
Storage
Store below 30°C, in a dry place, away from direct light. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is supportive and symptomatic; gastric lavage and activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy category C. Use during pregnancy only if clearly needed and the benefit outweighs the risk. Fexofenadine is excreted into breast milk; caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any excipients.
- Children under 6 years for 120mg/180mg tablets.
Drug Interactions
Erythromycin/Ketoconazole
Can increase plasma levels of fexofenadine, but generally without increased adverse effects.
Antacids (containing aluminum and magnesium)
May reduce the absorption of fexofenadine. Take antacids at least 2 hours apart from fexofenadine.
Storage
Store below 30°C, in a dry place, away from direct light. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, dizziness, and dry mouth. Management is supportive and symptomatic; gastric lavage and activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy category C. Use during pregnancy only if clearly needed and the benefit outweighs the risk. Fexofenadine is excreted into breast milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
Clinical Trials
Extensive clinical trials have established fexofenadine's efficacy and safety for allergic rhinitis and chronic urticaria across various patient populations.
Lab Monitoring
- No routine lab monitoring required for healthy individuals.
- Renal function monitoring in patients with impaired renal function.
Doctor Notes
- Advise patients to avoid taking fexofenadine with fruit juices as it can reduce drug efficacy.
- Fexofenadine is a good choice for patients requiring a non-sedating antihistamine.
Patient Guidelines
- Do not exceed the recommended dose.
- Avoid driving or operating machinery if you experience drowsiness.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally considered non-sedating, but individuals sensitive to antihistamines may experience drowsiness. Exercise caution until you know how it affects you.
Lifestyle Advice
- Identify and avoid known allergens.
- Keep indoor air clean to reduce exposure to dust mites and pollen.
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