Fexoral
Generic Name
Fexofenadine 30 mg Suspension
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fexoral 30 mg suspension | ৳ 48.00 | N/A |
Description
Overview of the medicine
Fexoral 30 mg Suspension contains Fexofenadine, a non-drowsy antihistamine used to relieve allergy symptoms such as runny nose, sneezing, itchy or watery eyes, and itching of the nose or throat. It is also used to treat chronic idiopathic urticaria (hives).
Uses & Indications
Dosage
Adults
Not typically used for adults in this specific suspension form. Adult dosage for tablets usually 60 mg twice daily or 120/180 mg once daily.
Renal_impairment
For children with impaired renal function, the recommended starting dose is 15 mg once daily for 2-11 years, and 7.5 mg once daily for 6 months-less than 2 years.
Children_2-5_years
15 mg (2.5 ml) twice daily.
Children_6-11_years
30 mg (5 ml) twice daily.
How to Take
Shake the suspension well before each use. Take orally with or without food. Avoid taking with fruit juices (grapefruit, orange, apple) as they may reduce absorption.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It prevents the effects of histamine released during allergic reactions, thus reducing symptoms like itching, sneezing, and watery eyes without causing significant sedation due to its poor ability to cross the blood-brain barrier.
Pharmacokinetics
Onset
Onset of action within 1 hour.
Excretion
Excreted primarily in the feces (approximately 80%) and urine (approximately 11%) as unchanged drug.
Half life
Approximately 14.4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached in approximately 2-3 hours.
Metabolism
Minimally metabolized; approximately 5% of the total dose is metabolized.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any component of the formulation.
Drug Interactions
Erythromycin and Ketoconazole
Can increase fexofenadine plasma concentrations, though generally not considered clinically significant.
Aluminum- and Magnesium-containing Antacids
May decrease fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children. Do not freeze.
Overdose
In case of overdose, symptoms may include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered. Hemodialysis does not effectively remove fexofenadine.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Side Effects
Contraindications
- Hypersensitivity to fexofenadine or any component of the formulation.
Drug Interactions
Erythromycin and Ketoconazole
Can increase fexofenadine plasma concentrations, though generally not considered clinically significant.
Aluminum- and Magnesium-containing Antacids
May decrease fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C. Protect from light and moisture. Keep out of reach of children. Do not freeze.
Overdose
In case of overdose, symptoms may include dizziness, drowsiness, and dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered. Hemodialysis does not effectively remove fexofenadine.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; caution should be exercised when administered to a nursing mother.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from the date of manufacture. Check product packaging for exact expiry date.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Fexofenadine has undergone extensive clinical trials demonstrating its efficacy and safety in treating seasonal allergic rhinitis and chronic idiopathic urticaria, including studies in pediatric populations.
Lab Monitoring
- Routine lab monitoring is not typically required.
Doctor Notes
- Emphasize the non-sedating nature of Fexofenadine, making it suitable for daytime use.
- Educate patients about the interaction with fruit juices to ensure optimal efficacy.
- Advise parents/caregivers on proper measuring techniques for pediatric suspension.
Patient Guidelines
- Follow the prescribed dosage and administration instructions.
- Shake the suspension well before each use.
- Avoid taking Fexoral with fruit juices (grapefruit, orange, apple).
- Inform your doctor about all other medications you are taking.
- If symptoms do not improve or worsen, consult your doctor.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Fexofenadine is generally non-sedating. However, individuals should ascertain their response to Fexoral before engaging in activities requiring mental alertness, such as driving or operating machinery.
Lifestyle Advice
- Identify and avoid known allergens to help manage allergy symptoms.
- Maintain good hydration.
- Avoid dusty or smoky environments if they trigger symptoms.
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