G-Salbutamol
Generic Name
Salbutamol
Manufacturer
Generic Pharmaceutical Co.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| g salbutamol 4 mg tablet | ৳ 0.46 | ৳ 4.60 |
Description
Overview of the medicine
Salbutamol 4 mg tablet is a fast-acting bronchodilator used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing, and shortness of breath. It works by relaxing the muscles of the airways to improve breathing.
Uses & Indications
Dosage
Adults
Typically 2 mg or 4 mg, 3 to 4 times a day, up to a maximum of 8 mg four times daily.
Elderly
Lower starting dose may be considered, e.g., 2 mg 3-4 times daily.
Renal_impairment
Dose adjustment may be necessary in severe renal impairment, monitor for side effects.
How to Take
Orally, with or without food. Swallow the tablet whole with water.
Mechanism of Action
Salbutamol selectively stimulates beta-2 adrenergic receptors in the smooth muscle of the bronchial tubes, causing bronchodilation by relaxing the smooth muscles and increasing cyclic AMP levels. This action helps to open the airways and ease breathing.
Pharmacokinetics
Onset
Oral: 30 minutes; Inhalation: 5-15 minutes
Excretion
Excreted primarily in the urine, both as unchanged drug and as the sulfate conjugate.
Half life
Oral: 4-6 hours
Absorption
Readily absorbed from the gastrointestinal tract; peak plasma concentrations achieved within 2-3 hours after oral administration.
Metabolism
Metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Thyrotoxicosis (relative contraindication, use with caution)
Drug Interactions
Digoxin
May decrease digoxin serum levels.
Diuretics
Increased risk of hypokalemia.
MAOIs/TCAs
Increased risk of cardiovascular effects.
Beta-blockers
May block the bronchodilatory effect of salbutamol and cause severe bronchospasm.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include tachycardia, tremor, headache, palpitation, and hypokalemia. Management is primarily supportive and symptomatic, possibly involving beta-blockers (cardioselective).
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted into breast milk; use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Thyrotoxicosis (relative contraindication, use with caution)
Drug Interactions
Digoxin
May decrease digoxin serum levels.
Diuretics
Increased risk of hypokalemia.
MAOIs/TCAs
Increased risk of cardiovascular effects.
Beta-blockers
May block the bronchodilatory effect of salbutamol and cause severe bronchospasm.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include tachycardia, tremor, headache, palpitation, and hypokalemia. Management is primarily supportive and symptomatic, possibly involving beta-blockers (cardioselective).
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted into breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date
Availability
Pharmacies, hospitals, clinics worldwide
Approval Status
Approved by major regulatory bodies (e.g., FDA, EMA, DGDA)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials have established the efficacy and safety of salbutamol in managing asthma and COPD symptoms.
Lab Monitoring
- Monitor serum potassium levels (especially in severe asthma or concomitant use of diuretics)
- Monitor blood glucose levels (especially in diabetics)
Doctor Notes
- Emphasize proper inhaler technique if concomitant inhalers are prescribed.
- Counsel patients on recognizing worsening asthma symptoms and when to seek urgent medical care.
- Be aware of potential drug interactions, especially with beta-blockers.
Patient Guidelines
- Do not exceed the prescribed dose.
- Carry your inhaler if you use one for quick relief.
- Report any worsening of symptoms or side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally safe, but be aware of potential side effects like tremor or dizziness that might affect driving or operating machinery. If affected, avoid such activities.
Lifestyle Advice
- Avoid triggers that worsen your asthma (e.g., smoke, allergens).
- Maintain a healthy lifestyle with regular exercise and a balanced diet.
- Quit smoking if applicable.
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Global Brand Names
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