g-Salbutamol
Generic Name
g-Salbutamol 5 mg Respirator Solution
Manufacturer
Generic Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| g salbutamol 5 mg respirator solution | ৳ 90.00 | N/A |
Description
Overview of the medicine
g-Salbutamol 5 mg Respirator Solution is a bronchodilator used to relieve symptoms of asthma and COPD, such as wheezing, shortness of breath, and chest tightness.
Uses & Indications
Dosage
Adults
2.5 mg or 5 mg, administered by nebulizer 3-4 times daily as needed. Can be diluted with normal saline.
Elderly
Same as adult dose, but caution is advised in patients with cardiovascular disease or other comorbidities.
Renal_impairment
No specific dose adjustment is usually required, but monitor for increased side effects with severe impairment.
How to Take
For inhalation use only, via a suitable nebulizer. Do not inject or swallow. Dilute with normal saline if required, as per medical advice.
Mechanism of Action
g-Salbutamol is a selective beta-2 adrenergic agonist. It acts on beta-2 receptors in the smooth muscle of the airways, causing relaxation of the muscles and bronchodilation. This opens the airways, making breathing easier.
Pharmacokinetics
Onset
5-15 minutes (inhalation)
Excretion
Excreted primarily in the urine, both as unchanged drug and metabolites.
Half life
Approximately 4-6 hours (systemic)
Absorption
After oral inhalation, a significant portion of the dose is deposited in the airways and absorbed into the systemic circulation. Some is swallowed and absorbed from the GI tract.
Metabolism
Primarily metabolized in the liver to an inactive sulfate conjugate.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Not for use in preterm labour or threatened abortion (unless specific indications related to uterine relaxation, which is a rare off-label use for acute situations)
Drug Interactions
Beta-blockers
May antagonize the effects of g-salbutamol and cause severe bronchospasm.
Diuretics (non-potassium-sparing)
Increased risk of hypokalemia, especially with high doses.
Tricyclic antidepressants and MAO inhibitors
Increased risk of cardiovascular side effects due to potentiated effects on the vascular system.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, hyperglycemia, and hypokalemia. Treatment is symptomatic and supportive; consider cardioselective beta-blockers with extreme caution.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit justifies the potential risk to the fetus (Category C). Small amounts may be excreted in breast milk; use with caution during lactation.
Side Effects
Contraindications
- Hypersensitivity to salbutamol or any component of the formulation
- Not for use in preterm labour or threatened abortion (unless specific indications related to uterine relaxation, which is a rare off-label use for acute situations)
Drug Interactions
Beta-blockers
May antagonize the effects of g-salbutamol and cause severe bronchospasm.
Diuretics (non-potassium-sparing)
Increased risk of hypokalemia, especially with high doses.
Tricyclic antidepressants and MAO inhibitors
Increased risk of cardiovascular side effects due to potentiated effects on the vascular system.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, palpitations, hyperglycemia, and hypokalemia. Treatment is symptomatic and supportive; consider cardioselective beta-blockers with extreme caution.
Pregnancy & Lactation
Use in pregnancy only if the potential benefit justifies the potential risk to the fetus (Category C). Small amounts may be excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months, refer to product packaging for specific dates.
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensively studied and widely used for decades. Ongoing research focuses on improved delivery methods and formulations.
Lab Monitoring
- Serum potassium levels (especially with high doses or concomitant diuretics)
- Blood glucose (in diabetic patients)
Doctor Notes
- Educate patients on proper nebulizer technique.
- Advise patients to seek immediate medical attention for worsening symptoms or paradoxical bronchospasm.
Patient Guidelines
- Always use as directed by your doctor or pharmacist.
- Do not exceed the recommended dose.
- Clean your nebulizer equipment regularly.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double dose.
Driving Precautions
May cause tremor or dizziness in some patients, which could impair the ability to drive or operate machinery. Exercise caution.
Lifestyle Advice
- Avoid smoking, as it can worsen respiratory conditions.
- Identify and avoid triggers that worsen your asthma or COPD.
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Global Brand Names
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